Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 608 findings · 115 reviews

No studies found 136 · 22.4%GRADE not reported 54 · 8.9%Very low 166 · 27.3%Low 152 · 25%Moderate 75 · 12.3%High 25 · 4.1%

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics

It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).

1 finding from 1 review

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Adverse events: hypotension · type 1 or type 2 diabetics

Blood pressure intervention/intensive blood pressure intervention may leads to higher adverse events—hypotension compared with placebo/standard blood pressure intervention (low certainty).

1 finding from 1 review

Intensive advocacy interventions for women who experience intimate partner abuse vs (Optimised) usual care

Physical abuse (dichotomous outcome) · women with intimate partner abuse

It is very uncertain whether intensive advocacy interventions for women who experience intimate… changes physical abuse (dichotomous outcome) compared with usual care at up to 12‐month follow‐up (very low certainty).

1 finding from 1 review

Intensive advocacy interventions for women who experience intimate partner abuse vs (Optimised) usual care

Emotional abuse (dichotomous outcome) · women with intimate partner abuse

Intensive advocacy interventions for women who experience intimate… showed no clear difference in emotional abuse (dichotomous outcome) compared with usual care at up to 12‐month follow‐up (moderate certainty).

1 finding from 1 review

Intensive advocacy interventions for women who experience intimate partner abuse vs (Optimised) usual care

Overall abuse One study used a composite of two scales (12 items. Scale from 0 to 36) Other study used Composite Abuse Scale (CAS)i (30 items presented in a 6‐point format requiring respondents to answer 'never', 'only once', 'several times', 'mon... · women with intimate partner abuse
1 finding from 1 review

Intensive advocacy interventions for women who experience intimate partner abuse vs (Optimised) usual care

Overall abuse (dichotomous outcome) · women with intimate partner abuse

It is very uncertain whether intensive advocacy interventions for women who experience intimate… changes overall abuse (dichotomous outcome) compared with usual care at up to 12‐month follow‐up (very low certainty).

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Diastolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in diastolic blood pressure (DBP, mmHg) compared with supra-gingival scaling (moderate certainty).

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Proportion of participants diagnosed with hypertension at trial completion · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

The review found no eligible studies for this question.

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Endothelial function (flow-mediated dilation) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to higher endothelial function (flow-mediated dilation) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Adverse events (participants with adverse events or withdrawals due to adverse events) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
1 finding from 1 review