Harms: pulmonary embolus or DVT · adults with or without existing CVD
It is very uncertain whether high changes harms: pulmonary embolus or DVT compared with low alpha‐linolenic acid omega‐3 fats (very low certainty).
1 finding from 1 review
ADHD symptoms – improvement – medium term · Children and adolescents with ADHD
Summary of findings table ‐ PUFA may leads to higher ADHD symptoms – improvement – medium term compared with placebo (low certainty).
1 finding from 1 review
ADHD symptoms · Children and adolescents with ADHD
1 finding from 1 review
ADHD symptoms – inattention, parent‐rated – medium term · Children and adolescents with ADHD
1 finding from 1 review
ADHD symptoms – hyperactivity/impulsivity, parent‐rated – medium term · Children and adolescents with ADHD
1 finding from 1 review
Side effects – overall · Children and adolescents with ADHD
Summary of findings table ‐ PUFA showed no clear difference in side effects – overall compared with placebo (moderate certainty).
1 finding from 1 review
Loss to · Children and adolescents with ADHD
Summary of findings table ‐ PUFA showed no clear difference in loss to compared with placebo (moderate certainty).
1 finding from 1 review
Depressive symptomology (continuous) HDRS where possible; higher scores indicate greater symptomology · adults with Major Depressive Disorder
1 finding from 1 review
Adverse events Study reports · adults with Major Depressive Disorder
It is very uncertain whether n3PUFAs changes adverse eventsStudy reports compared with placebo (very low certainty).
1 finding from 1 review
Depressive symptomology (dichotomous ‐ remission) Depressive symptomology rating scale as used by authors · adults with Major Depressive Disorder
n3PUFAs showed no clear difference in depressive symptomology (dichotomous ‐ remission)Depressive… compared with placebo (low certainty).
1 finding from 1 review
Depressive symptomology (dichotomous ‐ response) Depressive symptomology rating scale as used by authors · adults with Major Depressive Disorder
n3PUFAs showed no clear difference in depressive symptomology (dichotomous ‐ response)Depressive… compared with placebo (low certainty).
1 finding from 1 review
Quality of lifeValidated quality of life scales as used by authors, CGI (7‐point scale) where possible, higher scores indicate poorer quality of life · adults with Major Depressive Disorder
1 finding from 1 review
Trial non‐completionStudy reports · adults with Major Depressive Disorder
It is very uncertain whether n3PUFAs changes trial non‐completionStudy reports compared with placebo (very low certainty).
1 finding from 1 review
All‐cause mortality – deaths · adults with or without existing CVD
High showed no clear difference in all‐cause mortality – deaths compared with low long‐chain omega‐3 fats (high certainty).
1 finding from 1 review
Outcomes All in trials of 12 to 72 months' duration · adults with or without existing CVD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular mortality · adults with or without existing CVD
High probably leads to lower cardiovascular mortality – cardiovascular deaths compared with low long‐chain omega‐3 fats (moderate certainty).
1 finding from 1 review
Measures of adiposity – LCn3 – Weight, kg · adults with or without existing CVD
1 finding from 1 review
Body‐mass index (BMI) · adults with or without existing CVD
2 findings from 1 review
Serum total cholesterol – LCn3 – TC, mmol/L · adults with or without existing CVD
1 finding from 1 review
Serum fasting triglyceride (TG, mmol/L) · adults with or without existing CVD
1 finding from 1 review