Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

254 questions · 269 findings · 31 reviews

No studies found 34 · 12.6%GRADE not reported 3 · 1.1%Very low 70 · 26%Low 93 · 34.6%Moderate 44 · 16.4%High 25 · 9.3%

Fatty acid vs other topical intervention or standard care

Incidence of pressure ulcers · individuals at risk of pressure ulcer development

Fatty acid showed no clear difference in pressure ulcer incidence: fatty acid vs olive oil compared with other topical intervention or standard care (low certainty).

2 findings from 1 review

Fatty acid vs other topical intervention or standard care

Proportion of participants developing a new pressure ulcer · individuals at risk of pressure ulcer development

Fatty acid may leads to lower pressure ulcer incidence: fatty acid vs control compound compared with other topical intervention or standard care (low certainty).

2 findings from 1 review

Marine‐derived n‐3 fatty acids therapy vs No marine‐derived n‐3 fatty acids therapy

Efficacy (functional outcome) · stroke and/or TIA

It is very uncertain whether marine‐derived n‐3 fatty acids therapy changes primary outcome: efficacy (functional outcome) compared with no marine‐derived n‐3 fatty acids therapy (very low certainty).

2 findings from 1 review

Marine‐derived n‐3 fatty acids therapy vs No marine‐derived n‐3 fatty acids therapy

Recurrent events (both ischaemic and haemorrhagic stroke) · stroke and/or TIA

Marine‐derived n‐3 fatty acids therapy showed no clear difference in recurrent events (both ischaemic and haemorrhagic stroke) compared with no marine‐derived n‐3 fatty acids therapy (low certainty).

1 finding from 1 review

Marine‐derived n‐3 fatty acids therapy vs No marine‐derived n‐3 fatty acids therapy

Adverse events · stroke and/or TIA

Marine‐derived n‐3 fatty acids therapy showed no clear difference in adverse events compared with no marine‐derived n‐3 fatty acids therapy (low certainty).

2 findings from 1 review

Marine‐derived n‐3 fatty acids therapy vs No marine‐derived n‐3 fatty acids therapy

Recurrent events: fatal or non‐fatal (same type of stroke, i.e. ischaemic or haemorrhagic) · stroke and/or TIA

It is very uncertain whether marine‐derived n‐3 fatty acids therapy changes recurrent events: fatal or non‐fatal (same type of stroke, i.e.… compared with no marine‐derived n‐3 fatty acids therapy (very low certainty).

1 finding from 1 review

PUFA vs monounsaturated fatty acid (MUFA)

Global impression of deterioration (investigator defined global impression of deterioration) · people with multiple sclerosis

Polyunsaturated fatty acid (PUFA) showed no clear difference in global impression of deterioration (investigator defined global… compared with monounsaturated fatty acid (MUFA) (low certainty).

1 finding from 1 review