Question · asked by 1 review

PUFA vs monounsaturated fatty acid (MUFA): Relapse

It is very uncertain whether polyunsaturated fatty acid (PUFA) changes relapse(assessed as number of participants experiencing relapse) compared with monounsaturated fatty acid (MUFA) (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Polyunsaturated fatty acid (PUFA) vs monounsaturated fatty acid (MUFA)
Relapse(assessed as number of participants experiencing relapse) · adults with multiple sclerosis, defined by established criteria
It is very uncertain whether polyunsaturated fatty acid (PUFA) changes relapse(assessed as number of participants experiencing relapse) compared with monounsaturated fatty acid (MUFA) (very low certainty).
Dietary interventions for multiple sclerosis‐related outcomes (2020) · Cochrane Headline outcomes only
RR 1.02 [0.88, 1.2]3 studies · 217 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Dietary interventions for multiple sclerosis‐related outcomes
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.