Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,138 questions · 1,154 findings · 139 reviews · Headline outcomes only

No studies found 184 · 15.9%GRADE not reported 183 · 15.9%Very low 273 · 23.7%Low 296 · 25.6%Moderate 171 · 14.8%High 47 · 4.1%

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Satisfaction and acceptability of treatment (medium term) ‐ leaving the study early · people in the prodromal stage of psychosis

It is very uncertain whether group B antipsychotic drugs: olanzapine + supportive intervention changes satisfaction with treatment: leaving the study early Endpoint data… compared with placebo + supportive intervention (very low certainty).

1 finding from 1 review

Group B antipsychotic drugs: amisulpiride + needs‐focused intervention vs needs‐focused intervention

Satisfaction with treatment: leaving the study early Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group B antipsychotic drugs: amisulpiride + needs‐focused intervention changes satisfaction with treatment: leaving the study early Endpoint data… compared with needs‐focused intervention (very low certainty).

1 finding from 1 review

PFMT added to drug therapy vs drug therapy alone

Number of women cured · women with urinary incontinence

It is very uncertain whether PFMT added to drug therapy changes number of women cured ‐ PFMT + clenbuterol versus clenbuterol compared with drug therapy alone (very low certainty).

1 finding from 1 review

PFMT added to drug therapy vs drug therapy alone

Number of women reporting adverse events ‐ not reported · women with urinary incontinence

It is very uncertain whether PFMT added to drug therapy changes number of women reporting adverse events compared with drug therapy alone (very low certainty).

1 finding from 1 review

Dextrose gel vs placebo

Receipt of treatment for hypoglycaemia during initial hospital stay (investigator‐defined, any treatment ‐ oral dextrose gel, intravenous dextrose, or other drug therapy) during initial hospital stay (yes/no) · newborn infants at risk of neonatal hypoglycaemia

Dextrose gel showed no clear difference in receipt of treatment for hypoglycaemia during initial hospital stay… compared with placebo (moderate certainty).

1 finding from 1 review

Alpha2‐adrenergic agonist vs control

Bradycardia (requiring pharmacological or pacemaker treatment during the period of study drug administration) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists probably leads to higher bradycardia (requiring pharmacological or pacemaker treatment during… compared with control (moderate certainty).

1 finding from 1 review

Alpha2‐adrenergic agonist vs control

Hypotension (requiring treatment with inotropes or vasopressors during the period of study drug administration) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in hypotension (requiring treatment with inotropes or vasopressors… compared with control (low certainty).

1 finding from 1 review