Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

957 questions · 979 findings · 250 reviews

No studies found 159 · 16.2%GRADE not reported 75 · 7.7%Very low 264 · 27%Low 303 · 30.9%Moderate 138 · 14.1%High 40 · 4.1%

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐ patients considering the scar much better ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ 585‐nm pulsed‐dye laser (PDL) plus triamcinolone acetonide (TAC) plus 5‐Fluorouracil (5‐FU) versus TAC plus 5‐FU ‐ blinded observer assessment of good to excellent scar improvement ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ 585‐nm pulsed‐dye laser (PDL) plus triamcinolone… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ 585‐nm PDL plus TAC plus 5 FU versus TAC plus 5‐FU ‐ patient self‐assessment of good to excellent scar improvement ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ 585‐nm PDL plus TAC plus 5 FU versus TAC plus 5‐FU ‐… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Scar severity assessed by health professionals · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ Non‐Ablative Fractional Laser (NAFL) versus no… compared with no treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ Neodymium‐doped yttrium aluminium garnet (Nd:YAG) laser plus Diprospan plus 5‐FU versus Diprospan plus 5‐FU ‐ blinded observer assessment of good to excellent scar improvement ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ Neodymium‐doped yttrium aluminium garnet (Nd:YAG)… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity: Nd:YAG laser plus Diprospan plus 5‐FU versus Diprospan plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity: Nd:YAG laser plus Diprospan plus 5‐FU versus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Scar severity ‐ NAFL versus no treatment ‐ patient global assessment measured on a VAS ranging from 0 to 100 mm (0 = as normal skin and 100 = worst possible scar) ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, actual cases) Time of outcome assessment: short term (3 months postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Attitudes toward the duty to report child abuse and neglect Measured by: professionals’ self‐reported attitudes towards the duty to report child abuse and neglect Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, hypothetical vignette cases) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of reporting duty, processes, and procedures Measured by: professionals' self‐reported knowledge of jurisdictional or institutional reporting duties, or both Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of core concepts in child abuse and neglect (all forms) Measured by: professionals' self‐reported knowledge of all forms of child abuse and neglect (general measure) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of core concepts in child abuse and neglect (child sexual abuse only) Measured by: professionals' self‐reported knowledge of child sexual abuse (specific measure) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Skill in distinguishing between reportable and non‐reportable child abuse and neglect cases Measured by: professionals’ performance on simulated cases scored by trained and blinded expert panel Time of outcome assessment: short term (postintervent... · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Participant‐reported global assessment‐ total · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… probably leads to higher participant‐reported global assessment‐ total compared with land‐based exercise therapy (moderate certainty).

1 finding from 1 review