Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

236 questions · 244 findings · 40 reviews · Acute Respiratory Infections

No studies found 16 · 6.6%GRADE not reported 32 · 13.1%Very low 32 · 13.1%Low 60 · 24.6%Moderate 82 · 33.6%High 22 · 9%

Point‐of‐care biomarkers (procalcitonin) for infection vs usual care

Clinical recovery · people with acute respiratory infections

The review found no eligible studies for this question.

2 findings from 1 review

Point‐of‐care biomarkers (C‐reactive protein) for infection vs usual care

Clinical recovery · people with acute respiratory infections
2 findings from 1 review

Topical prophylaxis vs no topical prophylaxis

Respiratory tract infections ‐ topical plus systemic prophylaxis versus systemic prophylaxis alone · adults receiving mechanical ventilation for at least 48 hours

Topical prophylaxis showed no clear difference in respiratory tract infections ‐ topical plus systemic prophylaxis… compared with no topical prophylaxis (low certainty).

1 finding from 1 review

Topical prophylaxis vs no topical prophylaxis

Respiratory infections · adults receiving mechanical ventilation for at least 48 hours

Topical prophylaxis may leads to lower respiratory tract infections ‐ topical prophylaxis versus no… compared with no topical prophylaxis (low certainty).

2 findings from 1 review

Topical prophylaxis vs no topical prophylaxis

Dropouts due to adverse events · adults receiving mechanical ventilation for at least 48 hours

It is very uncertain whether topical prophylaxis changes dropouts due to adverse events compared with no topical prophylaxis (very low certainty).

1 finding from 1 review