What do systematic reviews say?

Intervention not reported

It is very uncertain whether the intervention changes acute renal injury, low‐risk studies only (very low certainty).

• Interventions for protecting renal function in the perioperative period 2013 · Cochrane Headline outcomes only
  OR 1.05 [0.55, 2.03]
  16 studies · 1550 participants
  Very low

Intervention not reported

The intervention showed no clear difference in perioperative bleeding requiring surgical intervention (moderate certainty).

• Nonsteroidal anti‐inflammatory drugs and perioperative bleeding in paediatric tonsillectomy 2013 · Cochrane Headline outcomes only
  OR 1.69 [0.71, 4.01]
  14 studies · 1044 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in perioperative bleeding requiring non‐surgical intervention (moderate certainty).

• Nonsteroidal anti‐inflammatory drugs and perioperative bleeding in paediatric tonsillectomy 2013 · Cochrane Headline outcomes only
  OR 0.99 [0.41, 2.4]
  10 studies · 745 participants
  Moderate

Intervention not reported

The intervention leads to lower vomiting (high certainty).

• Nonsteroidal anti‐inflammatory drugs and perioperative bleeding in paediatric tonsillectomy 2013 · Cochrane Headline outcomes only
  RR 0.72 [0.61, 0.85]
  13 studies · 1021 participants
  High

Intervention not reported

• Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
  no estimate extracted
  57 studies · 2902 participants
  Moderate

Intervention not reported

• Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 337 participants
  Moderate

Intervention not reported

• Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
  no estimate extracted
  30 studies · 1636 participants
  Low

Intervention not reported

• Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 395 participants
  Moderate

Paracervical vs placebo

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 381 participants
  High

Paracervical vs no anaesthesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 58 participants
  GRADE not reported
• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 58 participants
  GRADE not reported

Paracervical vs other regional anaesthesia

Paracervical block showed no clear difference in pain during the procedure compared with other regional anaesthesia (moderate certainty).

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  OR 1.41 [0.68, 2.91]
  1 study · 120 participants
  Moderate

Paracervical vs other regional anaesthesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 163 participants
  Low

Paracervical vs other regional anaesthesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 271 participants
  Very low

Paracervical vs other regional anaesthesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 307 participants
  High

Paracervical vs other regional anaesthesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 55 participants
  Low

Paracervical vs systemic analgesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 402 participants
  Low

Paracervical vs systemic analgesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 984 participants
  High

Paracervical vs systemic analgesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 166 participants
  Low

Paracervical vs placebo

Paracervical showed no clear difference in pain during uterine intervention ‐ Risk of any pain compared with placebo (low certainty).

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  RR 0.85 [0.54, 1.34]
  2 studies · 242 participants
  Low

Paracervical vs systemic analgesia

• Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 571 participants
  Low