Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,413 questions · 2,602 findings · 93 reviews · All outcomes

No studies found 452 · 17.4%GRADE not reported 1,582 · 60.8%Very low 392 · 15.1%Low 122 · 4.7%Moderate 53 · 2%High 1 · 0%

NobelReplace Select Tapered implants vs NobelReplace implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelReplace Select Tapered implants showed no clear difference in marginal bone level change compared with nobelReplace Groovy implants; GRADE not reported.

1 finding from 1 review

Thalidomide (systemic; 100 mg or 300 mg daily) vs placebo

Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Interventions for managing oral ulcers in Behçet's disease 2014 · Cochrane All outcomes
    Males only
    Hamuryudan 1998: significant adverse effects including severe sedation, polyneuropathy, loss of libido, and weight gain; a greater number of adverse events was seen for the higher (300 mg) dose; 4 patients withdrew due…
    1 study · 101 participants
    GRADE not reported

One-stage augmentation (implants placed simultaneously) vs Two-stage augmentation (delayed implant placement)

Implant failure · Patients with insufficient bone below the maxillary sinus requiring dental implants

One-stage augmentation (implants placed simultaneously) showed no clear difference in implant failure compared with two-stage augmentation (delayed implant placement); GRADE not reported.

1 finding from 1 review

NobelActive external connection implants vs NobelReplace implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in marginal bone level change compared with nobelReplace implants; GRADE not reported.

1 finding from 1 review

Osteotomes with mallet (Summers' technique) vs Rotary instruments (Cosci technique)

Complications · Patients undergoing crestal maxillary sinus lift

Osteotomes with mallet (Summers' technique) showed no clear difference in complications compared with rotary instruments (Cosci technique); GRADE not reported.

1 finding from 1 review

Sucralfate suspension (topical) vs Placebo suspension

Number of painful days · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Sucralfate suspension (topical) showed no clear difference in number of painful days compared with placebo suspension; GRADE not reported.

1 finding from 1 review

Steri-Oss acid-etched titanium screws vs Southern blasted/etched titanium screws

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Steri-Oss acid-etched titanium screws showed no clear difference in implant failure compared with southern blasted/etched titanium screws; GRADE not reported.

1 finding from 1 review

Southern regular implants vs Neoss turned implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Southern regular implants showed no clear difference in implant failure compared with neoss turned implants; GRADE not reported.

1 finding from 1 review

Colchicine (0.5 mg three times per day) vs placebo

Improvement in oral ulcer score · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Colchicine (systemic; 0.5 mg three times daily for 6 months) showed no clear difference in improvement in oral ulcer score compared with placebo; GRADE not reported.

1 finding from 1 review

One-stage lateral sinus lift with monocortical autogenous bone blocks (iliac crest) vs Two-stage lateral sinus lift with autogenous particulate bone (iliac crest)

Prosthesis failure · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor

One-stage lateral sinus lift with monocortical autogenous bone… showed no clear difference in prosthesis failure compared with two-stage lateral sinus lift with autogenous particulate bone (iliac…; GRADE not reported.

1 finding from 1 review

Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)

Complications · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)

Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in complications compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.

1 finding from 1 review

Hand mallet (osteotomes) vs Electric mallet

Complication at augmented site · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about 6.5 mm)

Hand mallet (osteotomes) showed no clear difference in complications at augmented site compared with electric mallet; GRADE not reported.

1 finding from 1 review

Autogenous bone graft (two-stage lateral sinus lift) vs Bone substitute (anorganic bovine bone / Bio-Oss)

Implant failure · Patients with an atrophic posterior maxilla requiring maxillary sinus augmentation

Autogenous bone graft (two-stage lateral sinus lift) showed no clear difference in implant failure compared with bone substitute (anorganic bovine bone / Bio-Oss); GRADE not reported.

1 finding from 1 review

NobelActive external connection implants vs NobelActive internal connection implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive external connection implants showed no clear difference in implant failure compared with nobelActive internal connection implants; GRADE not reported.

1 finding from 1 review