Cognitive deterioration · adults undergoing cardiac surgery with cardiopulmonary bypass
High showed no clear difference in cognitive deterioration compared with low blood pressure target (low certainty).
1 finding from 1 review
All‐cause mortality · adults undergoing cardiac surgery with cardiopulmonary bypass
It is very uncertain whether high changes all‐cause mortality compared with low blood pressure target (very low certainty).
1 finding from 1 review
Quality of life · adults undergoing cardiac surgery with cardiopulmonary bypass
It is very uncertain whether high changes quality of life compared with low blood pressure target (very low certainty).
1 finding from 1 review
Acute ischaemic stroke · adults undergoing cardiac surgery with cardiopulmonary bypass
It is very uncertain whether high changes acute ischaemic stroke compared with low blood pressure target (very low certainty).
1 finding from 1 review
Length of hospital stay · adults undergoing cardiac surgery with cardiopulmonary bypass
1 finding from 1 review
Perioperative transfusion of blood products · adults undergoing cardiac surgery with cardiopulmonary bypass
1 finding from 1 review
Red blood cell transfusions (Subnet based on 69 studies including 18,684 participants) · cardiac surgery for the treatment of non‐surgical bleeding
1 finding from 1 review
Blood products transfused (RBC) % of patients · cardiac surgery for the treatment of non‐surgical bleeding
It is very uncertain whether PCC changes blood products transfused (RBC) % of patients compared with FVIIa (very low certainty).
1 finding from 1 review
All thrombotic events (including myocardial infarction, ischaemic stroke, other arterial thromboembolism, and venous thromboembolism) · cardiac surgery for the treatment of non‐surgical bleeding
It is very uncertain whether PCC changes thrombotic events compared with FVIIa (very low certainty).
1 finding from 1 review
Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding
It is very uncertain whether PCC changes mortality (30‐day) compared with FVIIa (very low certainty).
1 finding from 1 review
Bleeding (chest drain output) in mLs for the first 12 hours · cardiac surgery for the treatment of non‐surgical bleeding
1 finding from 1 review
Length of critical care stay (hours) · cardiac surgery for the treatment of non‐surgical bleeding
1 finding from 1 review
Incidence of renal impairment · cardiac surgery for the treatment of non‐surgical bleeding
It is very uncertain whether PCC changes incidence of renal impairment compared with FVIIa (very low certainty).
1 finding from 1 review
Adverse events · cardiac surgery for the treatment of non‐surgical bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Blood products transfused (RBC) % of patients · cardiac surgery for the treatment of non‐surgical bleeding
PCC showed no clear difference in blood products transfused (RBC) % of patients compared with standard treatment (low certainty).
1 finding from 1 review
All thrombotic events (including myocardial infarction, ischaemic stroke, other arterial thromboembolism, and venous thromboembolism) · cardiac surgery for the treatment of non‐surgical bleeding
PCC showed no clear difference in thrombotic events compared with standard treatment (moderate certainty).
1 finding from 1 review
Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding
PCC showed no clear difference in mortality (30‐day) compared with standard treatment (moderate certainty).
1 finding from 1 review
Length of critical care stay (hours) · cardiac surgery for the treatment of non‐surgical bleeding
1 finding from 1 review
Incidence of renal impairment · cardiac surgery for the treatment of non‐surgical bleeding
PCC showed no clear difference in incidence of renal impairment compared with standard treatment (low certainty).
1 finding from 1 review
Bleeding (chest drain output) in mLs for the first 12 hours · cardiac surgery for the treatment of non‐surgical bleeding
1 finding from 1 review