Post‐insertion sensitivity or pain assessed by a validated pain scale · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review
Post‐insertion sensitivity or pain assessed by a validated pain scale - not measured | See comment | See comment | Not estimable | - | See comment | No study addressed this outcome
1 study · 31 participants
GRADE not reported
Tooth staining/discolouration (adverse effect) · Children and adolescents aged 16 years or less
1 finding from 1 review
Adverse effects · Children (permanent teeth; baseline 8 to 10 years)
1 finding from 1 review
Adverse effects · Children with permanent teeth (schoolchildren)
1 finding from 1 review
Unacceptability of treatment (dropouts/exclusions during the trial) · Children and adolescents aged 16 years or less
Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in unacceptability of treatment (dropouts/exclusions during the trial) compared with placebo or no treatment; GRADE not reported.
3 findings from 1 review
Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported
Adverse effects · Children (mixed dentition; baseline about 8 years)
1 finding from 1 review
Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · adults
1 finding from 1 review
Patterns of adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, and loose stool or diarrhoea) were similar for both groups. Bader 2013.
1 study · 669 participants
GRADE not reported
Staining · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Signs of acute toxicity during gel application (nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
It is very uncertain whether fluoride gel (topically applied; operator- or self-applied; any… changes signs of acute toxicity during gel application (nausea, gagging,… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Xylitol chewing gum vs No treatment or non-cariogenic control
Outcome not reported · Children and adults
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · Infants (primary teeth)
1 finding from 1 review
Costs (direct costs of interventions) · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects / specific side effects (oral allergic reactions, mucosal irritation, adverse symptoms such as nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
1 finding from 1 review
Patient's view and satisfaction with the treatment · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition
The review found no eligible studies for this question.
1 finding from 1 review
Postoperative sensitivity, marginal adaptation, anatomic form and other clinical outcomes (USPHS restoration quality; includes tooth vitality and pulpitis) · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition
The review found no eligible studies for this question.
1 finding from 1 review
Restoration survival · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition
The review found no eligible studies for this question.
1 finding from 1 review
Plaque · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)
It is very uncertain whether flossing plus toothbrushing (self-performed; manual or automated… changes plaque (Turesky-modified Quigley-Hein/other plaque indices; SMD) compared with toothbrushing alone (with or without a negative-control/placebo rinse) (very low certainty).
3 findings from 1 review
SMD -0.23 [-0.52, 0.06]
5 studies · 416 participants
Very low
SMD -0.06 [-0.23, 0.12]
3 studies · 487 participants
GRADE not reported
SMD -0.20 [-0.36, -0.04]
5 studies · 594 participants
GRADE not reported