Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Time to alignment · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Vibrational appliance with fixed appliances showed no clear difference in time to alignment (days) compared with fixed appliances only / no vibrational appliance (control); GRADE not reported.
1 finding from 1 review
MD -3.70 [-26.29, 18.89]
2 studies
GRADE not reported
Otitis media · patients with sore throat
Antibiotics leads to lower otitis media (within 14 days, clinical diagnosis) compared with control (high certainty).
1 finding from 1 review
Perioperative ipsilateral stroke (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Perioperative death from all causes (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Perioperative ipsilateral stroke (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Perioperative combined stroke and TIA (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Perioperative death from all causes (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Perioperative combined stroke and TIA (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Perioperative death from all causes (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Perioperative ipsilateral stroke (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Perioperative combined stroke and TIA (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…
1 finding from 1 review
Any stroke within 30 days of operation (primary outcome) · patients with symptomatic or asymptomatic carotid disease
1 finding from 1 review
Death within 30 days of operation · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in death within 30 days of operation compared with general anaesthesia (low certainty).
1 finding from 1 review
Perioperative ipsilateral stroke (< 30 days) · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in ipsilateral stroke within 30 days of operation compared with general anaesthesia (low certainty).
1 finding from 1 review
Perioperative death and strokes · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in stroke or death within 30 days of operation compared with general anaesthesia (moderate certainty).
1 finding from 1 review
Myocardial infarction (0 to 30 days) · patients with symptomatic or asymptomatic carotid disease
Local anaesthesia showed no clear difference in myocardial infarction within 30 days of operation compared with general anaesthesia (low certainty).
1 finding from 1 review
Bronchopulmonary dysplasia at 28 days · preterm infants
It is very uncertain whether prophylactic CPAP changes bronchopulmonary dysplasia at 28 days compared with very early CPAP (very low certainty).
1 finding from 1 review
Death at any time (by 28 days) · preterm infants
It is very uncertain whether prophylactic CPAP changes death at any time (by 28 days) compared with very early CPAP (very low certainty).
1 finding from 1 review