Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Posterior cruciate ligament retention vs sacrifice (using the same arthroplasty design)

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without resection of the posterior cruciate ligament for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs posterior stabilised sacrifice

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs sacrifice (all types of arthroplasty designs)

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

ANY INTERMITTENT DRUG TECHNIQUE vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

ANY INTERMITTENT DRUG TECHNIQUE probably leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (moderate certainty).

2 findings from 1 review

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Adverse effects: tardive dyskinesia: long term (+ 26 weeks) as defined in each study · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) showed no clear difference in adverse effects: tardive dyskinesia: long term (+26 weeks) as… compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review