Findings

What do systematic reviews say?

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

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No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Intervention not reported

Bleomycin (9 RCTs, 664 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 664 participants
Low

Intervention not reported

IPC – not daily drainage 6 RCTs, 587 participants · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 587 participants
Low

Intervention not reported

Doxycycline (1 RCT, 80 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Intervention not reported

Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Bleomycin (21 RCTs, 528 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
21 studies · 528 participants
Low

Intervention not reported

IPC –not daily drainage (6 RCTs, 405 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 405 participants
Moderate

Intervention not reported

Doxycycline (5 RCTs, 117 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 117 participants
Low

Intervention not reported

Placebo (4 RCTs, 159 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 159 participants
Moderate

Intervention not reported

Talc slurry (9 RCTs; 823 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

1 finding from 1 review

Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 823 participants
Low

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether triamcinolone acetonide 0.1% cream with occlusive dressing changes proportion of participants cleared or almost cleared ‐ compared with clobetasol cream 0.05% cream (very low certainty).

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
RR 1.2 [0.72, 2]
1 study · 19 participants
Very low

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants with adverse effects serious or severe enough to have caused withdrawal ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants with at least 50% improvement in their quality of life ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants achieving a 50% reduction in disease severity ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants without relapse in the long term ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Ease of compliance to an intervention or a treatment ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CBT with therapist support vs fatigue information leaflet only

Fatigue · IBD patients

2 findings from 1 review

Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low
Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

CBT with therapist support vs fatigue information leaflet only

Quality of life · IBD patients

1 finding from 1 review

Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

CBT with therapist support vs fatigue information leaflet only

Adverse events · IBD patients

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CBT with therapist support vs fatigue information leaflet only

Serious adverse events · IBD patients

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found