Findings

What do systematic reviews say?

3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only

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No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%

Acupuncture vs usual care

Physical quality of life · patients with non‐specific chronic low back pain

1 finding from 1 review

Acupuncture for chronic nonspecific low back pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 731 participants
Moderate

Acupuncture vs usual care

QoL: mental health SF‐12 (0 to 100; 0 = poor QoL, 100 = high QoL) · patients with non‐specific chronic low back pain

1 finding from 1 review

Acupuncture for chronic nonspecific low back pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 731 participants
Moderate

Acupuncture vs sham

QoL · patients with non‐specific chronic low back pain

1 finding from 1 review

Acupuncture for chronic nonspecific low back pain 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1068 participants
Low

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Global State: Average score (Role Functioning Scale, high = better functioning) · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

Exercise therapy vs psychological treatment

QoL · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Oral antibiotics vs placebo

Global change in composite ratings scale EASI ranges from 0 to 72 with higher values indicating greater severity. · people with atopic dermatitis

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Moderate

Bleach bath vs placebo or bath emollient

Change from baseline in quality of life CDLQI ranges from 0 to 30 with higher values indicating more impaired quality of life. · people with atopic dermatitis

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Moderate

Topical antibiotics with steroids vs topical steroid

Change from baseline in quality of life IDQoL ranges from 0 to 30 with higher values indicating more impaired quality of life · people with eczema

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Moderate

Bleach bath vs placebo or bath emollient

Global change in composite ratings scale EASI ranges from 0 to 72 with higher values indicating greater severity. · people with atopic dermatitis

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 54 participants
Very low

Topical antibiotics with steroids vs topical steroid

Global change in composite ratings scale EASI ranges from 0 to 72, objective SCORAD ranges from 0 to 83 and SCORAD ranges from 0 to 108, with higher values indicating greater severity. · people with eczema

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 256 participants
Low

Oral antibiotics vs placebo

Change from baseline in quality of life IDQoL ranges from 0 to 30 with higher values indicating more impaired quality of life. · people with atopic dermatitis

1 finding from 1 review

Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Moderate

Aerobic exercise vs no training

Aerobic capacity · people with dermatomyositis and polymyositis

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Exercise vs NSAIDs

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · young women with suspected primary dysmenorrhoea

1 finding from 1 review

Exercise for dysmenorrhoea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 122 participants
Very low

Exercise vs usual care

Beck Depression Inventory (BDI); higher score means more depression · people with ESKD

Exercise showed no clear difference in depression (any severity, including mild, moderate and severe… compared with usual care (moderate certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 108 participants
Moderate

Exercise vs usual care

Health‐related quality of lifeg Median · people with ESKD

Exercise may leads to higher HRQoL Investigators measured health related quality of life using… compared with usual care (low certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
MD 3.06 [2.29, 3.83]
2 studies · 64 participants
Low

CBT vs usual care

Depressive symptoms · people with ESKD

Cognitive‐behavioural therapy showed no clear difference in depression (any severity, including mild, moderate and severe… compared with usual care (moderate certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 230 participants
Moderate

Relaxation vs usual care

Depressive symptoms · people with ESKD

Relaxation techniques showed no clear difference in depression (any severity, including mild, moderate and severe… compared with usual care (moderate certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 122 participants
Moderate

Spiritual practice vs usual care

Beck Depression Inventory (BDI); higher score means more depression · people with ESKD

It is very uncertain whether spiritual practice changes depression (any severity, including mild, moderate and severe… compared with usual care (very low certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 116 participants
Very low

Counselling vs usual care

Depressive symptoms · people with ESKD

Counselling showed no clear difference in depression (any severity, including mild, moderate and severe… compared with usual care (low certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 99 participants
Low

Stem cell transplantation vs Conventional treatment

Neurologic impairment (measured by NIHSS; 0 to 42; higher = worse) · ischemic stroke

1 finding from 1 review

Stem cell transplantation for ischemic stroke 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 319 participants
Low