Overall survival (total mortality), chemotherapy regimen A vs regimen B · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
1 finding from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
Non-selective carious tissue removal and conventional restoration (CR) may leads to higher failure of therapy compared with hall Technique (sealing with a preformed metal crown) (low certainty).
1 finding from 1 review
Chemotherapy vs Placebo
Outcome not reported · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
The review found no eligible studies for this question.
1 finding from 1 review
Overall survival, induction platinum + 5-fluorouracil prior to radiotherapy vs radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (moderate certainty).
1 finding from 1 review
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower disease-free survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
Efficiency, costs or cost-effectiveness · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review
Locoregional control · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower locoregional control, concurrent chemoradiotherapy (platinum +… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
RR 0.75 [0.61, 0.93]
3 studies
GRADE not reported
Overall survival, post-surgery chemotherapy vs surgery alone (no radiotherapy) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Surgery +/- radiotherapy + (adjuvant) chemotherapy showed no clear difference in overall survival, adjuvant chemotherapy vs observation alone… compared with surgery +/- radiotherapy alone (observation or adjuvant radiotherapy… (moderate certainty).
1 finding from 1 review
Nausea · women undergoing regional anaesthesia for caesarean section
5‐HT3 antagonists may leads to lower nausea ‐ intraoperative compared with placebo (low certainty).
2 findings from 1 review
Vomiting ‐ intraoperative · women undergoing regional anaesthesia for caesarean section
It is very uncertain whether corticosteroids changes vomiting ‐ intraoperative compared with placebo (very low certainty).
1 finding from 1 review
Nausea · women undergoing regional anaesthesia for caesarean section
Corticosteroids probably leads to lower nausea ‐ postoperative compared with placebo (moderate certainty).
2 findings from 1 review
Vomiting ‐ postoperative · women undergoing regional anaesthesia for caesarean section
Corticosteroids may leads to lower vomiting ‐ postoperative compared with placebo (low certainty).
1 finding from 1 review
Nausea · women undergoing regional anaesthesia for caesarean section
Anticholinergics may leads to lower nausea ‐ intraoperative compared with placebo (low certainty).
2 findings from 1 review
Vomiting ‐ intraoperative · women undergoing regional anaesthesia for caesarean section
It is very uncertain whether anticholinergics changes vomiting ‐ intraoperative compared with placebo (very low certainty).
1 finding from 1 review
Vomiting ‐ intraoperative · women undergoing regional anaesthesia for caesarean section
It is very uncertain whether 5‐HT3 antagonists changes vomiting ‐ intraoperative compared with placebo (very low certainty).
1 finding from 1 review
Vomiting ‐ postoperative · women undergoing regional anaesthesia for caesarean section
Anticholinergics may leads to lower vomiting ‐ postoperative compared with placebo (low certainty).
1 finding from 1 review
Nausea · women undergoing regional anaesthesia for caesarean section
Sedatives probably leads to lower nausea ‐ intraoperative compared with placebo (moderate certainty).
2 findings from 1 review
Vomiting ‐ intraoperative · women undergoing regional anaesthesia for caesarean section
Sedatives probably leads to lower vomiting ‐ intraoperative compared with placebo (moderate certainty).
1 finding from 1 review
Vomiting ‐ postoperative · women undergoing regional anaesthesia for caesarean section
Sedatives may leads to lower vomiting ‐ postoperative compared with placebo (low certainty).
1 finding from 1 review
Nausea · women undergoing regional anaesthesia for caesarean section
It is very uncertain whether acupressure/acupuncture changes nausea ‐ intraoperative compared with placebo (very low certainty).
2 findings from 1 review