Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,256 questions · 2,339 findings · 262 reviews

No studies found 555 · 23.7%GRADE not reported 398 · 17%Very low 572 · 24.5%Low 476 · 20.4%Moderate 240 · 10.3%High 98 · 4.2%

Infiltration injection local anaesthetic vs no treatment or placebo

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Lip or cheek biting, numbness or allergy · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Postoperative pain · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Nocturnal ventilation vs no ventilation

Mortality at 1 year (or more) · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether nocturnal ventilation changes mortality at 1 year (or more) compared with no ventilation (very low certainty).

1 finding from 1 review

Nocturnal ventilation vs no ventilation

Unplanned admission to hospital · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether nocturnal ventilation changes unplanned admission to hospital compared with no ventilation (very low certainty).

1 finding from 1 review

Nocturnal ventilation vs no ventilation

No improvement of hypoventilation symptoms: long‐term · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether nocturnal ventilation changes no improvement of hypoventilation symptoms: long‐term compared with no ventilation (very low certainty).

1 finding from 1 review

Nocturnal ventilation vs no ventilation

No improvement of daytime hypercapnia: long‐term · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether nocturnal ventilation changes no improvement of daytime hypercapnia: long‐term compared with no ventilation (very low certainty).

1 finding from 1 review

Volume‐cycled ventilation vs pressure‐cycled ventilation

Mortality at 1 year (or more) Not measured ‐ data reported for mortality at 3 months · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether volume‐cycled ventilation changes mortality at 1 year (or more) Not measured ‐ data reported for… compared with pressure‐cycled ventilation (very low certainty).

1 finding from 1 review

Volume‐cycled ventilation vs pressure‐cycled ventilation

No improvement of hypoventilation symptoms: long‐term ‐ not measured · patients with neuromuscular and chest wall disorders and chronic hypoventilation

The review found no eligible studies for this question.

1 finding from 1 review

Volume‐cycled ventilation vs pressure‐cycled ventilation

No improvement of daytime hypercapnia: long‐term ‐ not measured · patients with neuromuscular and chest wall disorders and chronic hypoventilation

The review found no eligible studies for this question.

1 finding from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Postoperative mortality · adult participants given general anaesthesia

It is very uncertain whether PEEP changes postoperative mortality compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review