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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
274 questions in 25 reviews · Movement Disorders
current versionsNo studies 13 · 4.7%Ungraded 7 · 2.6%Very low 66 · 24.1%Low 66 · 24.1%Moderate 87 · 31.8%High 35 · 12.8%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BoNT‐A/OT vs Placebo/no treatment Goal attainment Goal Attainment Scaling3. Scale from: 20 to 80. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 33 participants | High |
BoNT‐A/OT vs Placebo/no treatment Occupational performance ‐ performance Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 35 participants | High |
BoNT‐A/OT vs Placebo/no treatment Occupational performance ‐ satisfaction Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 35 participants | High |
BoNT‐A only vs OT only Elbow flexor spasticity modified Tardieu scale. Scale from: 0 to 180. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 35 participants | High |
BoNT‐A vs Placebo/no treatment Quality of movement (18 mths ‐ 8yrs) Quality of Upper Extremity Skills Test. Scale from: 0 to 100. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 13 participants | Moderate |
BoNT‐A only vs OT only Wrist flexor spasticity modified Tardieu scale. Scale from: 0 to 90. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 35 participants | Moderate |
BoNT‐A only vs OT only Quality of movement (18 mths ‐ 8yrs) QUEST. Scale from: 0 to 100. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 13 participants | Moderate |
BoNT‐A only vs OT only Quality of movement (5 yrs ‐ 15yrs) The Melbourne Assessment. Scale from: 0 to 100. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 21 participants | Moderate |
BoNT‐A only vs OT only Goal attainment Goal attainment scaling3. Scale from: 20 to 80. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 36 participants | Moderate |
BoNT‐A only vs OT only Occupational performance ‐ performance Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 36 participants | Moderate |
BoNT‐A only vs OT only Occupational performance ‐ satisfaction Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 36 participants | Moderate |
High dose BoNT‐A vs Low dose BoNT‐A Elbow flexor spasticity · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
High dose BoNT‐A vs Low dose BoNT‐A Wrist flexor spasticity · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
High dose BoNT‐A vs Low dose BoNT‐A Quality of movement (18 mths ‐ 8yrs) Quality of Upper Extremity Skills Test. Scale from: 0 to 100. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 39 participants | Moderate |
High dose BoNT‐A vs Low dose BoNT‐A Goal attainment · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
BoNT‐A vs Placebo/no treatment Quality of movement (5 yrs ‐ 15yrs) The Melbourne Assessment. Scale from: 0 to 100. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 21 participants | Moderate |
High dose BoNT‐A vs Low dose BoNT‐A Quality of movement (5 yrs to 15 yrs) · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
High dose BoNT‐A vs Low dose BoNT‐A Occupational performance ‐ performance · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
High dose BoNT‐A vs Low dose BoNT‐A Occupational performance ‐ satisfaction · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
BoNT‐A vs Placebo/no treatment Goal attainment Goal Attainment Scaling3. Scale from: 20 to 80. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 32 participants | Moderate |
BoNT‐A vs Placebo/no treatment Occupational performance ‐ performance Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 34 participants | High |
BoNT‐A vs Placebo/no treatment Occuptional performance ‐ satisfaction Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 34 participants | High |
BoNT‐A/OT vs OT only Elbow flexor spasticity modified Tardieu scale. Scale from: 0 to 180. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 36 participants | High |
BoNT‐A/OT vs OT only Wrist flexor spasticity modified Tardieu scale. Scale from: 0 to 90. · children with cerebral palsy Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic… (2010) · Cochrane | no estimate extracted | 1 study · 36 participants | High |