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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

775 questions in 58 reviews · Bone, Joint and Muscle Trauma

current versions
No studies 166 · 21.4%Ungraded 24 · 3.1%Very low 356 · 45.9%Low 162 · 20.9%Moderate 47 · 6.1%High 20 · 2.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Timing of wound closure (immediate vs delayed)
Return to work by 12 months · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
HRQoL at 6 or 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Deep surgical site infection at 30 days or 90 days, or time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Delayed or non‐union at time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Unplanned operations at 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events: superficial infection · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
RR 1.19 [0.49, 2.87]1 study · 77 participantsVery low
Intervention NR
Return to work by 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Timing of wound closure (immediate vs delayed)
Limb function at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Timing of wound closure (immediate vs delayed)
HRQoL at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Open reduction vs closed reduction position
Functional outcome · children with displaced supracondylar elbow fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
no estimate extractedNRNo studies
Surgical fixation vs non‐surgical immobilisation
Cosmetic deformity measured as presence of cubitus varus · children with displaced fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
RR 0.2 [0.04, 1.09]NRVery low
Open reduction vs closed reduction position
Treatment failure requiring re‐intervention · children with displaced supracondylar elbow fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
no estimate extractedNRNo studies
Open reduction vs closed reduction position
Nerve injury · children with displaced supracondylar elbow fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
RR 0.3 [0.09, 1.01]NRLow
Open reduction vs closed reduction position
Major complications · children with displaced supracondylar elbow fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
RR 4.15 [1.07, 16.2]NRLow
Open reduction vs closed reduction position
Cosmetic deformity Measured as the presence of cubitus varus · children with displaced supracondylar elbow fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
no estimate extractedNRNo studies
Surgical fixation vs non‐surgical immobilisation
Functional outcome · children with displaced fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
no estimate extractedNRNo studies
Surgical fixation vs non‐surgical immobilisation
Treatment failure requiring re‐intervention · children with displaced fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
RR 0.33 [0.01, 7.87]NRVery low
Surgical fixation vs non‐surgical immobilisation
Nerve injury · children with displaced fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
RR 2.5 [0.5, 12.46]NRVery low
Surgical fixation vs non‐surgical immobilisation
Major complications Pin site infections. · children with displaced fractures
Interventions for treating supracondylar elbow fractures in children (2022) · Cochrane
RR 4 [0.47, 34.11]NRVery low
Multidisciplinary inpatient rehabilitation vs usual care
'Poor outcome' (dead or deterioration in residential status, generally requiring institutional care) · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.88 [0.8, 0.98]13 studies · 3036 participantsModerate
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
'Poor outcome' (dead or moved to higher level of care or unable to walk) · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.91 [0.62, 1.35]3 studies · 377 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Quality of life: SF‐36 Physical Component score (0: worst to 100: best) · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extracted1 study · 56 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Mortality (at 4 months) · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.77 [0.34, 1.76]2 studies · 275 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Mortality (end of scheduled · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 1 [0.61, 1.63]3 studies · 377 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Independent in personal activities of daily living · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 1.06 [0.71, 1.57]1 study · 159 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Permanent move to higher level of care (hostel, nursing home, sheltered housing) · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.35 [0.07, 1.69]2 studies · 168 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Unable to walk · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.89 [0.38, 2.04]2 studies · 214 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: mainly
Pain (end of · older people, mainly living in the community, undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extractedNRNo studies
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
'Poor outcome' (dead or unable to walk) · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 1.04 [0.87, 1.24]1 study · 240 participantsLow
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Quality of life: EQ‐5D (0: dead to 1: best quality)c · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extracted1 study · 235 participantsVery low
Multidisciplinary inpatient rehabilitation vs usual care
Quality of life: EQ‐5D (0: dead to 1: best quality)c · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extracted1 study · 347 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Mortality (at 4 months) · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 1.05 [0.7, 1.56]1 study · 240 participantsLow
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Mortality (end of scheduled · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 1.13 [0.86, 1.49]1 study · 240 participantsLow
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Functional dependency: modified Barthel Index (0 to 100: total independence in personal care) · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extracted1 study · 202 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Functional dependency: modified Barthel Index (0 to 100: total independence in personal care) · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extracted1 study · 125 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Unable to walk · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.89 [0.38, 2.04]1 study · 130 participantsVery low
Supported discharge and multidisciplinary home rehabilitation vs usual care: people living
Pain: PAINAD (0 to 10; severest pain) · older people from nursing homes undergoing rehabilitation after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extracted1 study · 126 participantsVery low
Multidisciplinary inpatient rehabilitation vs usual care
Mortality (at discharge) · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.77 [0.58, 1.04]11 studies · 2455 participantsLow
Multidisciplinary inpatient rehabilitation vs usual care
Mortality (end of scheduled · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.91 [0.8, 1.05]18 studies · 3973 participantsLow
Multidisciplinary inpatient rehabilitation vs usual care
Greater dependence in personal activities of daily livingg · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.87 [0.76, 0.99]4 studies · 754 participantsVery low
Multidisciplinary inpatient rehabilitation vs usual care
Greater dependence in personal activities of daily livingg · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.64 [0.51, 0.81]2 studies · 238 participantsVery low
Multidisciplinary inpatient rehabilitation vs usual care
Greater dependency in mobility (e.g. requiring help by another person) · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.83 [0.71, 0.98]5 studies · 1085 participantsLow
Multidisciplinary inpatient rehabilitation vs usual care
Hip‐related pain · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
no estimate extractedNRNo studies
Multidisciplinary inpatient rehabilitation vs usual care
Delirium in hospitalj · older people undergoing rehabilitation soon after surgically treated hip fracture
Multidisciplinary rehabilitation for older people with hip fractures (2021) · Cochrane
RR 0.85 [0.74, 0.98]4 studies · 980 participantsLow
Percutaneous patellar osteosynthesis vs open surgery
Patient‐rated knee function score assessed using the Lysholm Knee Scoring Scale (0–100; 100 = best function). · adults with fractures of the patella
Interventions for treating fractures of the patella in adults (2021) · Cochrane
no estimate extracted1 study · 52 participantsVery low
Percutaneous patellar osteosynthesis vs open surgery
Anterior knee pain measured using VAS: 0 to 10 cm (10 cm = worst score) · adults with fractures of the patella
Interventions for treating fractures of the patella in adults (2021) · Cochrane
no estimate extracted4 studies · 183 participantsVery low
Percutaneous patellar osteosynthesis vs open surgery
Major adverse outcome: total events · adults with fractures of the patella
Interventions for treating fractures of the patella in adults (2021) · Cochrane
RR 0.26 [0.14, 0.46]3 studies · 145 participantsVery low
Percutaneous patellar osteosynthesis vs open surgery
Observer‐rated measures of knee function Knee function scores (see comment) · adults with fractures of the patella
Interventions for treating fractures of the patella in adults (2021) · Cochrane
SMD 1.01 [0.08, 1.95]3 studies · 124 participantsVery low
Percutaneous patellar osteosynthesis vs open surgery
Health‐related quality of life · adults with fractures of the patella
Interventions for treating fractures of the patella in adults (2021) · Cochrane
no estimate extractedNRNo studies
Percutaneous patellar osteosynthesis vs open surgery
Return to previous activity · adults with fractures of the patella
Interventions for treating fractures of the patella in adults (2021) · Cochrane
no estimate extractedNRNo studies