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What do systematic reviews say?

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Evidence found and GRADE certainty

1,655 questions · 1,751 findings · 147 reviews · Pain, Palliative and Supportive Care

No studies found 361 · 20.6%GRADE not reported 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%

Intervention not reported

Cessation of pain at end of treatmenta · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…
1 finding from 1 review

Intervention not reported

Retreatment with the same intervention at 0 to 1 hour · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Retreatment with the alternative intervention at 0 to 1 hour · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Dermatological signs up to 1 week after the sting · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…

The review found no eligible studies for this question.

1 finding from 1 review

Application of heat vs application of cold

Adverse events due to treatment Minor adverse events, reported in studies as: exacerbation in pain after treatment; burn as a result of hot‐water immersion, or transient erythema, or adverse effects due to application of ice · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes adverse events due to treatment Minor adverse events, reported in… compared with application of cold (very low certainty).

1 finding from 1 review

Application of heat vs application of cold

Clinically significant reduction in pain · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes clinically significant reduction in pain at 0 to 1 hour Reported in… compared with application of cold (very low certainty).

1 finding from 1 review

Application of heat vs application of cold

Cessation of pain at end of treatmenta · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes cessation of pain at end of treatmentb compared with application of cold (very low certainty).

1 finding from 1 review

Application of heat vs application of cold

Retreatment with the same intervention · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes retreatment with the same intervention compared with application of cold (very low certainty).

1 finding from 1 review

Application of heat vs application of cold

Retreatment with the alternative treatment (heat or cold application) at 0 to 1 hour · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes retreatment with the alternative treatment (heat or cold… compared with application of cold (very low certainty).

1 finding from 1 review

Application of heat vs application of cold

Dermatological signs up to 1 week after the sting · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes dermatological signs up to 1 week after the sting Reported in… compared with application of cold (very low certainty).

1 finding from 1 review

Intervention not reported

At least a clinically significant reduction in pain within 6 hours Reported in study as complete cessation of pain.a · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…
1 finding from 1 review

Intervention not reported

Adverse events due to treatment · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…
1 finding from 1 review

Intervention not reported

Pain intensity measured on CHQ (0‐100; 0 = worse pain), and VAS (0 to 100; 0 = no pain) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review