Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

236 questions · 242 findings · 34 reviews · Headline outcomes only

No studies found 85 · 35.1%GRADE not reported 4 · 1.7%Very low 58 · 24%Low 52 · 21.5%Moderate 36 · 14.9%High 7 · 2.9%

Zinc vs placebo

BMD Z score (total hip/femoral neck) · children and adults with β‐thalassaemia major and low bone mass

Summary of findings – zinc probably leads to higher BMD Z score (total hip/femoral neck) compared with placebo (moderate certainty).

1 finding from 1 review

Zinc vs placebo

BMD Z score (lumbar spine) · children and adults with β‐thalassaemia major and low bone mass

Summary of findings – zinc probably leads to higher BMD Z score (lumbar spine) compared with placebo (moderate certainty).

1 finding from 1 review