Intervention not reported
Portocaval shunt(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention probably leads to lower portocaval shunt(No direct RCT) (moderate certainty).
1 finding from 1 review
HR 0.21 [0.05, 0.77]
Studies not reported
Moderate
Intervention not reported
Beta‐blockers(1 RCT; 65 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention may leads to higher beta‐blockers(1 RCT; 65 participants) (low certainty).
1 finding from 1 review
Intervention not reported
Beta‐blockers plus Sclerotherapy(8 RCTs; 370 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention showed no clear difference in beta‐blockers plus Sclerotherapy(8 RCTs; 370 participants) (low certainty).
1 finding from 1 review
HR 0.69 [0.43, 1.09]
Studies not reported
Low
Intervention not reported
No active intervention(4 RCTs; 412 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention showed no clear difference in no active intervention(4 RCTs; 412 participants) (low certainty).
1 finding from 1 review
HR 1.2 [0.83, 1.84]
Studies not reported
Low
Intervention not reported
TIPS(3 RCTs; 189 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention showed no clear difference in TIPS(3 RCTs; 189 participants) (low certainty).
1 finding from 1 review
HR 0.94 [0.56, 1.59]
Studies not reported
Low
Intervention not reported
Beta‐blockers plus Nitrates(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention showed no clear difference in beta‐blockers plus Nitrates(No direct RCT) (low certainty).
1 finding from 1 review
HR 0.91 [0.53, 1.58]
Studies not reported
Low
Intervention not reported
Portocaval shunt(2 RCTs; 100 participants) · people with liver cirrhosis and previous oesophageal variceal bleeding
The intervention showed no clear difference in portocaval shunt(2 RCTs; 100 participants) (low certainty).
1 finding from 1 review
HR 1.21 [0.68, 2.15]
Studies not reported
Low
All‐cause mortality · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
It is very uncertain whether sclerotherapy changes all‐cause mortality compared with no intervention (very low certainty).
1 finding from 1 review
Upper gastrointestinal bleeding · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
It is very uncertain whether sclerotherapy changes upper gastrointestinal bleeding compared with no intervention (very low certainty).
1 finding from 1 review
Serious adverse events and liver‐related morbidity: incidence of congestive hypertensive gastropathy · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
It is very uncertain whether sclerotherapy changes serious adverse events and liver‐related morbidity: incidence of… compared with no intervention (very low certainty).
1 finding from 1 review
Health‐related quality of life · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐serious adverse events · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
1 finding from 1 review
Outcomes* · adults with oesophageal varices
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · adults with oesophageal varices
Band ligation probably leads to lower mortality compared with no intervention (moderate certainty).
1 finding from 1 review
Upper gastrointestinal bleeding · adults with oesophageal varices
Band ligation probably leads to lower upper gastrointestinal bleeding compared with no intervention (moderate certainty).
1 finding from 1 review
Serious adverse events · adults with oesophageal varices
Band ligation probably leads to lower serious adverse events compared with no intervention (moderate certainty).
1 finding from 1 review
Non‐serious adverse events · adults with oesophageal varices
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · adults with oesophageal varices
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · adults with cirrhosis and gastroesophageal varices
Carvedilol showed no clear difference in mortality compared with traditional, non‐selective beta‐blockers (low certainty).
1 finding from 1 review
Upper gastrointestinal bleeding · adults with cirrhosis and gastroesophageal varices
It is very uncertain whether carvedilol changes upper gastrointestinal bleeding compared with traditional, non‐selective beta‐blockers (very low certainty).
1 finding from 1 review