Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

304 questions · 314 findings · 29 reviews · Public Health

No studies found 57 · 18.2%GRADE not reported 22 · 7%Very low 88 · 28%Low 86 · 27.4%Moderate 43 · 13.7%High 18 · 5.7%

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Anaemia · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… may leads to lower anaemia (defined as haemoglobin below the WHO cut‐off, adjusted for… compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Iron deficiency (as defined by study authors, based on a biomarker of iron status) · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… may leads to lower iron deficiency (as defined by study authors, based on a biomarker… compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Vitamin A deficiency · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… showed no clear difference in vitamin A deficiency (as defined by the study authors) compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Any adverse effects (hookworm infection risk) · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… may leads to higher any adverse effects (hookworm infection risk) compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Diarrhoea · general population of all age groups (including pregnant women) from any country, over two years of age

It is very uncertain whether rice fortified with iron alone or in combination with other… changes diarrhoea (as defined by study authors) compared with unfortified rice (no micronutrients added) (very low certainty).

1 finding from 1 review

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

Anaemia · general population older than 2 years of age (including pregnant women), in Kenya and Mexico

It is very uncertain whether provision of maize flour or maize flour products fortified with iron… changes anaemia (defined as haemoglobin (Hb) below WHO cut‐off, adjusted for… compared with unfortified maize flours or maize flour products (very low certainty).

1 finding from 1 review

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

Iron deficiency (as defined by study authors, based on a biomarker of iron status) · general population older than 2 years of age (including pregnant women), in Kenya and Mexico

It is very uncertain whether provision of maize flour or maize flour products fortified with iron… changes iron deficiency (as defined by trialists, based on a biomarker of… compared with unfortified maize flours or maize flour products (very low certainty).

1 finding from 1 review

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

Any adverse effects (including constipation, nausea, vomiting, heartburn or diarrhoea, as measured by trialists) · general population older than 2 years of age (including pregnant women), in Kenya and Mexico

The review found no eligible studies for this question.

1 finding from 1 review

Foods fortified with zinc alone vs same foods without adding zinc

Stunting · general population of all age groups (including pregnant women) from any country, over two years of age

Foods fortified with zinc alone showed no clear difference in stunting (author defined) compared with same foods without adding zinc (low certainty).

1 finding from 1 review

Foods fortified with zinc alone vs same foods without adding zinc

Underweight · general population of all age groups (including pregnant women) from any country, over two years of age

Foods fortified with zinc alone showed no clear difference in underweight (author defined) compared with same foods without adding zinc (low certainty).

1 finding from 1 review

Foods fortified with zinc plus other micronutrients vs foods fortified with other micronutrients without zinc

Zinc deficiency (as defined by authors, depending on age and gender) · general population of all age groups (including pregnant women) from any country, over two years of age

It is very uncertain whether foods fortified with zinc plus other micronutrients changes zinc deficiency (as defined by authors, depending on age and gender) compared with foods fortified with other micronutrients without zinc (very low certainty).

1 finding from 1 review