evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

161 questions · 170 findings · 38 reviews · Neonatal

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 22 · 12.9%GRADE not reported 2 · 1.2%Very low 38 · 22.4%Low 66 · 38.8%Moderate 31 · 18.2%High 11 · 6.5%

NIPPV vs NCPAP

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · )

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in severe intraventricular hemorrhage (grade III/IV) compared with nasal continuous positive airway pressure (NCPAP) (by population) (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Death or bronchopulmonary dysplasia at 36 weeks PMA · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes death or BPD at 36 weeks PMA compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

BPD at 28 days · health problem or population

The review found no eligible studies for this question.

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

BPD (36 weeks' PMA) · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes BPD, defined as supplemental oxygen or positive pressure support use… compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Treatment failure or need for mechanical ventilation · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes treatment failure or need for mechanical ventilation compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Mortality before hospital discharge · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes mortality, by hospital discharge compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Moderate‐severe neurodevelopmental impairment at 18 to 26 months ‐ not measured · health problem or population

The review found no eligible studies for this question.

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Bronchopulmonary dysplasia/chronic lung disease · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes BPD, defined as supplemental oxygen or positive pressure support use… compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Combined outcome of mortality or BPD at 36 weeks' PMA · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes death or BPD at 36 weeks' PMA compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Superoxide dismutase (SOD) vs placebo

Severe retinopathy of prematurity (stage II or greater)№ of participants: 244(1 RCT) · preterm infants at risk for bronchopulmonary dysplasia

It is very uncertain whether superoxide dismutase (SOD) changes severe retinopathy of prematurity (stage II or greater)№ of… compared with placebo (very low certainty).

1 finding from 1 review