Admission to neonatal intensive care unit · women in the third trimester for induction of labour with intact membranes
1 finding from 1 review
Vaginal birth within 24 hours · induction of labour.
Oral misoprostol 20 µg hourly titrated showed no clear difference in vaginal birth within 24 hours compared with oral misoprostol 25 µg two‐hourly static (low certainty).
1 finding from 1 review
Caesarean section · induction of labour.
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes caesarean section compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
1 finding from 1 review
Uterine hyperstimulation with fetal heart rate changes · induction of labour.
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
1 finding from 1 review
Oxytocin augmentation · induction of labour.
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes oxytocin augmentation compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
1 finding from 1 review
Uterine hyperstimulation without fetal heart rate changes · induction of labour.
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · induction of labour.
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes apgar score less than 7 at 5 minutes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
1 finding from 1 review
Admission to neonatal intensive care unit · induction of labour.
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes admission to NICU compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
1 finding from 1 review
Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who required a further dose of either the same sedative agent or the addition of a different sedative agent · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg + 50 mg/kg) showed no clear difference in proportion of children who had sedation failure or inadequate level… compared with hydroxyzine hydrochloride oral (1 mg/kg + 1 mg/kg) (low certainty).
1 finding from 1 review
Sedation duration (minutes) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Number of children with clinical adverse event: behavioural change · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg + 50 mg/kg) showed no clear difference in number of children with clinical adverse event: behavioural change compared with hydroxyzine hydrochloride oral (1 mg/kg + 1 mg/kg) (low certainty).
1 finding from 1 review
Number of children with clinical adverse event: nausea or vomiting · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg + 50 mg/kg) showed no clear difference in number of children with clinical adverse event: nausea or vomiting compared with hydroxyzine hydrochloride oral (1 mg/kg + 1 mg/kg) (low certainty).
1 finding from 1 review
Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who required a further dose of either the same sedative agent or the addition of a different sedative agent · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children with inadequate level of sedation (Ramsay score below 4) · children undergoing neurodiagnostic procedures
Chloral hydrate oral (100 mg/kg or 75 mg/kg) probably leads to lower proportion of children with inadequate level of sedation (Ramsay… compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (moderate certainty).
1 finding from 1 review