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Evidence found and GRADE certainty

1,103 questions · 1,157 findings · 177 reviews · Headline outcomes only

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No studies found 291 · 25.2%GRADE not reported 85 · 7.3%Very low 317 · 27.4%Low 258 · 22.3%Moderate 169 · 14.6%High 37 · 3.2%

Zuclopenthixol dihydrochloride vs RISPERIDONE

Adverse effects: Clinically important general adverse effect ‐ short term (EPSEs requiring medication) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect ‐ short… compared with risperidone (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs sulpiride

Global state: Average endpoint global state score (clinically improved) (CGI ‐ unchanged/worse) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes global state: Average endpoint global state score (clinically… compared with sulpiride (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs sulpiride

Adverse effects: Clinically important general adverse effect ‐ requiring hypnotics/sedatives · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect ‐… compared with sulpiride (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs OTHER ANTIPSYCHOTIC: h. THIOTHIXENE

Global state: Average endpoint global state score (clinically improved) (CGI ‐ unchanged/worse) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes global state: Average endpoint global state score (clinically… compared with thiothixene (very low certainty).

1 finding from 1 review