Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

111 questions · 123 findings · 10 reviews · Gynaecology and Fertility

No studies found 21 · 17.1%GRADE not reported 1 · 0.8%Very low 34 · 27.6%Low 49 · 39.8%Moderate 18 · 14.6%High 0 · 0%

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Pregnancy loss · ovarian stimulation protocols for women undergoing ART

Progestogen showed no clear difference in pregnancy loss (Prog + Ag vs Ag) compared with placebo or no pretreatment (low certainty).

2 findings from 1 review

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

OHSS · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Pregnancy loss · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in pregnancy loss (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Multiple pregnancy rate · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

OHSS · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in OHSS rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Intervention not reported

Live birth ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower live birth ‐ Clomiphene citrate 5 days versus clomiphene citrate 10… (low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (low certainty).

1 finding from 1 review

Intervention not reported

Multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether the intervention changes multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (very low certainty).

1 finding from 1 review

Intervention not reported

Miscarriage rate ‐ Early versus late clomiphene citrate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether the intervention changes miscarriage rate ‐ Early versus late clomiphene citrate (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy ‐ Early versus late clomiphene citrate · ovulation induction in polycystic ovarian syndrome

The intervention may leads to higher clinical pregnancy ‐ Early versus late clomiphene citrate (low certainty).

1 finding from 1 review