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Evidence found and GRADE certainty

369 questions · 377 findings · 28 reviews · Schizophrenia

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No studies found 101 · 26.8%GRADE not reported 54 · 14.3%Very low 133 · 35.3%Low 63 · 16.7%Moderate 26 · 6.9%High 0 · 0%

NIDOTHERAPY‐ENHANCED STANDARD CARE vs usual care

Adverse effect: Specific ‐ Death · schizophrenia

It is very uncertain whether NIDOTHERAPY‐ENHANCED STANDARD CARE changes adverse effects ‐ specific ‐ death Number of individual deaths of… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

Group B cognitive behavioural therapy: cognitive behavioural therapy + supportive therapy vs supportive therapy

Prodromal symptoms: transition to psychosis Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes prodromal symptoms: transition to psychosis Long‐term (events) compared with supportive therapy (very low certainty).

1 finding from 1 review

Group B cognitive behavioural therapy: cognitive behavioural therapy + supportive therapy vs supportive therapy

Satisfaction and acceptability of treatment (medium term) ‐ leaving the study early · people in the prodromal stage of psychosis

It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes satisfaction with treatment: leaving the study early Endpoint data… compared with supportive therapy (very low certainty).

1 finding from 1 review

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Global impression: 1. Not able to be discharged (long term) · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY may leads to higher global impression: 1. Not able to be discharged (long term) compared with MEDICATION (low certainty).

1 finding from 1 review

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Global impression: 2. Given medication during 12 months to three years · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY may leads to lower global impression: 2. Given medication during 12 months to three years compared with MEDICATION (low certainty).

2 findings from 1 review

Horticultural therapy plus standard care vs usual care

Well‐being and quality of life Personal Wellbeing Index (PWI‐C) . Scale from: 0 to 77 (low = poor) · patients with schizophrenia

It is very uncertain whether horticultural therapy plus standard care changes well‐being and quality of life Personal Wellbeing Index (PWI‐C) .… compared with standard care alone (very low certainty).

1 finding from 1 review

Horticultural therapy plus standard care vs usual care

Satisfaction with treatment: leaving the study early Endpoint data (events) · patients with schizophrenia

It is very uncertain whether horticultural therapy plus standard care changes satisfaction with treatment Leaving the study early compared with standard care alone (very low certainty).

1 finding from 1 review