Serious adverse events (range of outcomes) · adult women diagnosed with early stage (I to IIa) endometrial cancer undergoing surgery as primary treatment.
Laparoscopy showed no clear difference in serious adverse events (range of outcomes) compared with laparotomy (low certainty).
1 finding from 1 review
Rate of symptom relief · women previously treated for endometrial cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Rate of tumour recurrence · women previously treated for endometrial cancer
It is very uncertain whether oestrogen replacement therapy changes rate of tumour recurrence compared with placebo (very low certainty).
1 finding from 1 review
Rate of appearance of a new malignancy · women previously treated for endometrial cancer
It is very uncertain whether oestrogen replacement therapy changes rate of appearance of a new malignancy compared with placebo (very low certainty).
1 finding from 1 review
Rate of survival: overall survival · women previously treated for endometrial cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression‐free survival (PSF) · women previously treated for endometrial cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall survival · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes overall survival compared with stereotactic radiosurgery (very low certainty).
1 finding from 1 review
Health‐related quality of life (HRQoL) · people with single or solitary brain metastasis
1 finding from 1 review
Adverse events · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events compared with stereotactic radiosurgery (very low certainty).
1 finding from 1 review
Adverse events (moderate) · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery (very low certainty).
1 finding from 1 review
Adverse events (severe) · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (severe) compared with stereotactic radiosurgery (very low certainty).
1 finding from 1 review
Progression‐free survival ‐ not measured · people with single or solitary brain metastasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life (HRQoL) · people with single or solitary brain metastasis
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low
Overall survival · people with single or solitary brain metastasis
Surgery plus whole brain radiotherapy (WBRT) showed no clear difference in overall survival compared with stereotactic radiosurgery plus WBRT (low certainty).
1 finding from 1 review
Adverse events (moderate) · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery plus WBRT (very low certainty).
1 finding from 1 review
Progression‐free survival · people with single or solitary brain metastasis
Surgery plus whole brain radiotherapy (WBRT) showed no clear difference in progression‐free survival compared with stereotactic radiosurgery plus WBRT (low certainty).
1 finding from 1 review
Overall survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in overall survival compared with WBRT (moderate certainty).
1 finding from 1 review
Disease‐specific survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in disease‐specific survival compared with WBRT (moderate certainty).
1 finding from 1 review
Local tumor control · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) probably leads to lower local tumor control compared with WBRT (moderate certainty).
1 finding from 1 review
Functionally independent survival (KPS) · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in functionally independent survival (KPS) compared with WBRT (moderate certainty).
1 finding from 1 review