Cochrane · systematic review · CD006655
Laparoscopy versus laparotomy for the management of early stage endometrial cancer
Galaal, K, Donkers, H, Bryant, A, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Gynaecological, Neuro-oncology and Orphan CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Laparoscopy versus laparotomy for early stage endometrial cancer
Population: adult women diagnosed with early stage (I to IIa) endometrial cancer undergoing surgery as primary treatment.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival (survival until death from all causes) Laparoscopy vs laparotomy | HR 1.04 [0.86, 1.25] | 6 studies · 3993 participants | Moderate Downgraded: risk of bias, imprecision |
Recurrence free survival Laparoscopy vs laparotomy | HR 1.14 [0.9, 1.43] | 5 studies · 3710 participants | Moderate Downgraded: risk of bias, imprecision |
Serious adverse events (range of outcomes) Laparoscopy vs laparotomy | no estimate extracted | 8 studies · 313 participants | Low Downgraded: risk of bias, imprecision |