Restoration failure · Children with carious primary teeth after vital or non-vital pulp therapy
In one RCT, composite strip crowns with composite posts had an annual failure rate of 2.3% after 1 year.
1 finding from 1 review
Cost of the intervention · People with a permanent tooth that has undergone endodontic (root canal) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Patient satisfaction / quality of life (validated measure) · People with a permanent tooth that has undergone endodontic (root canal) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Catastrophic failure of the restored tooth or restoration leading directly to extraction · People with a permanent tooth that has undergone endodontic (root canal) treatment
1 finding from 1 review
SoF 'Catastrophic failure of restoration': assumed risk (conventional filling) 0, corresponding risk (single crown) 0; no events in either group so a relative effect was not estimable; 117 participants (1 study); GRADE…
1 study · 117 participants
Very low
Periodontal health status · People with a permanent tooth that has undergone endodontic (root canal) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Non-catastrophic failure of the post · People with a permanent tooth that has undergone endodontic (root canal) treatment
It is very uncertain whether single full-coverage metal-ceramic crown over composite core and post changes non-catastrophic failure of the post compared with direct adhesive composite restoration with post (conventional… (very low certainty).
1 finding from 1 review
Incidence or recurrence of caries (assessed clinically or by radiographs) · People with a permanent tooth that has undergone endodontic (root canal) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Non-catastrophic failure of the restoration (requiring further treatment) · People with a permanent tooth that has undergone endodontic (root canal) treatment
It is very uncertain whether single full-coverage metal-ceramic crown over composite core and post changes non-catastrophic failure of the restoration (requiring further… compared with direct adhesive composite restoration with post (conventional… (very low certainty).
1 finding from 1 review
Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures
1 finding from 1 review
Hodosh 2003 (Analysis 3.1): all 18 patients receiving KNO3/DMI/PCa responded favourably (0/18 developed clinical symptoms) versus 9/17 in the KNO3/PCa group; symptomatic teeth required endodontic therapy or extraction.…
1 study · 35 participants
GRADE not reported
Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures
1 finding from 1 review
Hodosh 2003 (Analysis 3.1): all 18 patients receiving KNO3/DMI/PCa responded favourably (0/18 developed clinical symptoms) versus 10/12 in the PCa group. "The results in groups two and three were statistically…
1 study · 30 participants
GRADE not reported
Enamel remineralization / carious lesion development · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, an ammonium-based methacrylate-containing adhesive showed significant remineralization/anti-demineralization versus control in a single study (ungraded).
1 finding from 1 review
Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
17 findings from 1 review
Show 14 more findings
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Dentine-caries (D3) prevalence low <15% (non-CBCT)
Sensitivity 0.36 [0.25, 0.47]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: excavation (non-CBCT)
Sensitivity 0.51 [0.27, 0.74]
5 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Analogue and digital combined (non-CBCT); 97 datasets
Sensitivity 0.46 [0.40, 0.51]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Dentine-caries (D3) prevalence high >=35% or unreported (non-CBCT)
Sensitivity 0.50 [0.40, 0.59]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: low risk of bias for index test
Sensitivity 0.51 [0.43, 0.61]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: excluding high/unclear risk of bias reference standard
Sensitivity 0.51 [0.45, 0.57]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Setting: in vivo / clinical (non-CBCT)
Sensitivity 0.56 [0.43, 0.69]
17 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Setting: in vitro (non-CBCT)
Sensitivity 0.44 [0.37, 0.50]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: low dentine-caries prevalence <15%
Sensitivity 0.34 [0.25, 0.45]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: histology (non-CBCT)
Sensitivity 0.46 [0.39, 0.53]
64 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies)
Sensitivity 0.47 [0.40, 0.53]
77 studies
Low
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Occlusal surfaces (non-CBCT)
Sensitivity 0.45 [0.35, 0.54]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Primary dentition (non-CBCT)
Sensitivity 0.52 [0.40, 0.63]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Proximal surfaces (non-CBCT)
Sensitivity 0.47 [0.39, 0.55]
Studies not reported
GRADE not reported
Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
17 findings from 1 review
Show 14 more findings
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Setting: in vitro (non-CBCT)
Specificity 0.89 [0.84, 0.92]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Proximal surfaces (non-CBCT)
Specificity 0.89 [0.84, 0.93]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Primary dentition (non-CBCT)
Specificity 0.87 [0.77, 0.93]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Occlusal surfaces (non-CBCT)
Specificity 0.88 [0.80, 0.93]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: excluding high/unclear risk of bias reference standard
Specificity 0.87 [0.83, 0.90]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: excavation (non-CBCT)
Specificity 0.96 [0.80, 0.99]
5 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Dentine-caries (D3) prevalence medium 15-34% (non-CBCT)
Specificity 0.87 [0.78, 0.92]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies)
Specificity 0.88 [0.84, 0.92]
77 studies
Low
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Analogue and digital combined (non-CBCT); 97 datasets
Specificity 0.89 [0.86, 0.92]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: low dentine-caries prevalence <15%
Specificity 0.91 [0.87, 0.94]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Dentine-caries (D3) prevalence low <15% (non-CBCT)
Specificity 0.91 [0.85, 0.95]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Setting: in vivo / clinical (non-CBCT)
Specificity 0.89 [0.78, 0.95]
17 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: enhanced visual (non-CBCT)
Specificity 0.91 [0.77, 0.97]
8 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: histology (non-CBCT)
Specificity 0.88 [0.83, 0.92]
64 studies
GRADE not reported
Diagnostic accuracy on surfaces with pit and fissure sealants · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
The review found no eligible studies for this question.
1 finding from 1 review
Diagnostic accuracy in previously restored teeth (secondary caries) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
The review found no eligible studies for this question.
1 finding from 1 review
Restoration failure · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth
No dentinal caries removal (caries sealed under a preformed metal… probably leads to lower failure of restorations compared with complete caries removal (moderate certainty).
1 finding from 1 review
Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth
No dentinal caries removal (caries sealed under a preformed metal… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (moderate certainty).
1 finding from 1 review
A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique
Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of anterior teeth, irrespective of…
The review found no eligible studies for this question.
1 finding from 1 review
A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique
Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of posterior teeth, irrespective of…
The review found no eligible studies for this question.
1 finding from 1 review
Peri-implant clinical and radiographic parameters (plaque index, probing depth, bone loss, pro-inflammatory profile) · Adult e-cigarette (ENDS) users with dental implants (incl. male implant-supported prosthesis patients)
Among dental implant patients, e-cigarette users show worse peri-implant parameters (more plaque, worse clinical and radiographic outcomes) than non-smokers (narrative synthesis; ungraded).
1 finding from 1 review