Periodontitis and allostatic load · US adults in NHANES III
Allostatic load partly explained socioeconomic gradients in periodontal disease.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in total mortality compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).
1 finding from 1 review
Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in locoregional recurrence compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review
Periodontitis and allostatic load · US adults in NHANES 1999-2004
Allostatic load increased the probability of periodontitis and the association varied by race/ethnicity.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Caries experience (mean DMFT) · Adults aged 19-60 years
Pooled caries experience (DMFT) was similar in very-high-HDI and high-HDI countries, and meta-regression found no significant association between national HDI and DMFT; ungraded observational evidence with very high heterogeneity.
3 findings from 1 review
Discriminant power for caries severity: effect size (f) for microbial load (log10 CFU) between lesion categories · Patients with dentine carious lesions (deciduous/permanent teeth; children and adults)
The weighted effect size favoured hardness (f=2.62) over colour (f=0.46) for discriminating microbial load, supporting hardness as the more reliable examination (ungraded).
1 finding from 1 review
Discriminant power for caries severity: mean difference in log10 CFU (microbial load) between lesion categories · Patients with dentine carious lesions (deciduous/permanent teeth; children and adults)
For yellow-vs-other colour compared with soft-vs-harder hardness, hardness was significantly the more discriminant test (pooled WMD -3.87, 95% CI -4.46 to -2.87; ungraded).
6 findings from 1 review
WMD -3.867 [-4.461, -2.874]
2 studies
GRADE not reported
WMD -4.446 [-5.241, -3.650]
2 studies
GRADE not reported
WMD -0.067 [-1.877, 1.743]
2 studies
GRADE not reported
Show 3 more findings
Only one study (Beighton et al.) permitted this comparison: the mean log10 CFU difference was 2.32 for the colour contrast (black vs rest) versus 3.72 for the hardness contrast (soft vs medium/hard); hardness appeared…
1 study
GRADE not reported
WMD -4.741 [-4.979, -4.502]
2 studies
GRADE not reported
WMD -3.369 [-3.595, -3.143]
2 studies
GRADE not reported
Caries experience (mean DMFT) · Adults aged 19-60 years
The proportion of university-educated people was not associated with caries experience (DMFT); pooled DMFT was similar across subgroups and the meta-regression was non-significant; ungraded observational evidence.
5 findings from 1 review
Show 2 more findings
Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol significantly reduced Mutans streptococci in dental plaque compared with no treatment (SMD -0.73, 95% CI -1.09 to -0.37; 5 trials, I2=53%; not GRADE-rated).
1 finding from 1 review
Dental caries: dmfs increment (primary teeth) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Proportion developing new caries · Children and adolescents aged 16 years or less
Fluoride mouthrinse (any fluoride agent, concentration, volume,… showed no clear difference in proportion of children developing one or more new caries compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
1 finding from 1 review
One trial (Rugg-Gunn 1973) reported incompletely on oral soft tissue irritation/signs of sensitivity (allergic reaction): "no cases of mucosal hypersensitivity after periodical examinations of every subject". 434…
1 study · 434 participants
Very low
Signs of acute toxicity during gel application (nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
It is very uncertain whether fluoride mouthrinse (any fluoride agent, concentration, volume,… changes unacceptability of treatment as measured by leaving study early… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Proportion of children not remaining caries-free · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review