Intervention not reported
Bleomycin (21 RCTs, 528 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
IPC –not daily drainage (6 RCTs, 405 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Doxycycline (5 RCTs, 117 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Placebo (4 RCTs, 159 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Talc slurry (9 RCTs; 823 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Ambulation · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes ambulation At four months compared with radiotherapy (very low certainty).
1 finding from 1 review
Survival At four months · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes survival At four months compared with radiotherapy (very low certainty).
1 finding from 1 review
Reduced use of analgesics · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes reduction in analgesic use compared with radiotherapy (very low certainty).
1 finding from 1 review
Urinary continence One month after radiation · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
It is very uncertain whether laminectomy plus radiotherapy changes urinary continence One month after treatment compared with radiotherapy (very low certainty).
1 finding from 1 review
Local recurrence · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
1 finding from 1 review
Quality of life · adults with metastatic extradural spinal cord compression (single lesion, no prior radiotherapy, fit for surgery)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ambulation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
Decompressive surgery plus radiotherapy may leads to higher ambulation Immediately after completing RT compared with radiotherapy (low certainty).
1 finding from 1 review
Survival (short term) At 30 days · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
Decompressive surgery plus radiotherapy showed no clear difference in survival (short term) At 30 days compared with radiotherapy (low certainty).
1 finding from 1 review
Reduction in analgesic and narcotic use One month after radiation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
1 finding from 1 review
Urinary continence 3 months after surgery MCID: 5% absolute difference · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
1 finding from 1 review
Local recurrence · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
1 finding from 1 review
Quality of life · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Total studies: 42 Total participants: 14,626 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
The intervention led to lower total studies: 42 Total participants: 14,626; GRADE not reported.
1 finding from 1 review
no estimate extracted
42 participants
GRADE not reported