Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and TotalFill BC had comparable pulpotomy success (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Mature permanent teeth with irreversible pulpitis and carious pulp exposure (treated with full pulpotomy)
Platelet-rich fibrin and calcium hydroxide showed no significant difference in success (ungraded; effect size not reported).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and calcium-enriched mixture had comparable pulpotomy success (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and platelet-rich fibrin had comparable pulpotomy success (ungraded).
1 finding from 1 review
Tooth survival · Children with carious vital pulp exposure in primary incisors
Tooth survival was reported narratively in two trials and was not pooled.
1 finding from 1 review
Pathological periapical radiolucency · Children with carious vital pulp exposure in primary incisors
Two trials reported periapical radiolucency but results were not pooled owing to considerable heterogeneity.
1 finding from 1 review
Clinical failure · Children with carious vital pulp exposure in primary incisors
Pulpotomy may not differ from pulpectomy for clinical failure; no GRADE rating was reported.
1 finding from 1 review
Soft tissue pathology · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in soft tissue pathology between pulpotomy and pulpectomy (RR 3.11, 95% CI 0.54 to 17.7; ungraded).
1 finding from 1 review
RR 3.11 [0.54, 17.7]
Studies not reported
GRADE not reported
Pathological mobility · Children with carious vital pulp exposure in primary incisors
Pathological mobility was rare (one tooth in one of four trials) and was not pooled.
1 finding from 1 review
Pathological root resorption · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in pathological root resorption between pulpotomy and pulpectomy (RR 1.5, 95% CI 0.56 to 4.04; ungraded).
1 finding from 1 review
RR 1.5 [0.56, 4.04]
2 studies
GRADE not reported
Radiographic failure · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in radiographic failure between pulpotomy and pulpectomy in the main analysis (RR 0.79, 95% CI 0.25 to 2.42), with considerable heterogeneity (I2=76%; ungraded).
2 findings from 1 review
Pain · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in pain between pulpotomy and pulpectomy (RR 2.06, 95% CI 0.31 to 13.8; ungraded).
1 finding from 1 review
RR 2.06 [0.31, 13.8]
Studies not reported
GRADE not reported
Pulp canal obliteration · Children with carious vital pulp exposure in primary incisors
Pulp canal obliteration was reported narratively (mainly in the pulpotomy group) and was not pooled.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
The effect of MTA versus CH after pulpotomy is uncertain (low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth undergoing pulpotomy
The two trials of PRF versus MTA for success gave contradictory results and were not pooled (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
MTA and CEM performed comparably for clinical and radiographic success (2 RCTs, not pooled; ungraded).
1 finding from 1 review
Dentin bridge formation · Patients with carious pulp exposure in permanent teeth undergoing partial pulpotomy
Evidence on dentin bridge formation for calcium hydroxide versus MTA is weak and imprecise, with no material shown superior (4 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth
In immature teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 2.22, 95% CI 0.13-36.67; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping
For direct pulp capping, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.10, 95% CI 1.66-5.79; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth of mixed/unspecified root maturation
In mixed-maturation teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 1.11, 95% CI 0.17-7.11; very low certainty).
1 finding from 1 review