Endoscopic improvement (dichotomous) · Adult patients with active ulcerative colitis
Budesonide MMX® 9 mg showed no clear difference in endoscopic improvement compared with entocort EC 9mg (moderate certainty).
1 finding from 1 review
Endoscopic remission · Adult patients with active ulcerative colitis
Budesonide MMX® 9 mg probably leads to higher endoscopic remission compared with placebo (moderate certainty).
1 finding from 1 review
Remission (combined clinical and endoscopic remission) · Adult patients with active ulcerative colitis
Budesonide MMX® 6 mg showed no clear difference in remission (combined clinical and endoscopic remission compared with placebo (low certainty).
1 finding from 1 review
Failure to induce endoscopic remission · patients with induction of remission in ulcerative colitis
Etrolizumab showed no clear difference in failure to enter endoscopic remission at week 6 compared with placebo (moderate certainty).
2 findings from 1 review
Rebleeding · patients with upper gastrointestinal bleeding
Tranexamic acid may leads to lower rebleeding Clinical and endoscopic assessment compared with placebo (low certainty).
1 finding from 1 review
Rebleeding · patients with upper gastrointestinal bleeding
Tranexamic acid probably leads to lower rebleeding Clinical and endoscopic assessment compared with cimetidine or lansoprazole (moderate certainty).
1 finding from 1 review
Failure to induce endoscopic remission · Patients with moderately to severely active ulcerative colitis
Vedolizumab leads to lower failure to induce endoscopic remission compared with placebo (high certainty).
1 finding from 1 review
Endoscopic relapse · Patients with moderately to severely active ulcerative colitis
Vedolizumab probably leads to lower endoscopic relapse compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Gastric outlet obstruction Clinical symptoms of vomiting with confirmation of the gastric outlet obstruction by radiological or endoscopic investigations · patients with unresectable periampullary carcinoma
It is very uncertain whether the intervention changes gastric outlet obstruction Clinical symptoms of vomiting with… (very low certainty).
1 finding from 1 review
Endoscopic remission · Patients with quiescent ulcerative colitis
Rectal 5‐ASA showed no clear difference in endoscopic remission compared with oral 5‐ASA (low certainty).
1 finding from 1 review
Endoscopic Index at 6 months Endoscopic Index9. Scale from: 1 to 4. · Maintenance of remission in ulcerative colitis
1 finding from 1 review
Mortality ‐ within 30 days · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in mortality ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Rebleeding · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in rebleeding ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Surgery ‐ within 30 days · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in surgery ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Proportion of participants with stigmata of recent haemorrhage at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in proportion of participants with stigmata of recent haemorrhage at… compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Technical success in insertion
Electromagnetic‐guided showed no clear difference in technical success in insertion compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (low certainty).
1 finding from 1 review
Aspiration pneumonitis
Electromagnetic‐guided showed no clear difference in aspiration pneumonitis compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (low certainty).
1 finding from 1 review
Time for postpyloric placement of nasoenteral feeding tubes (minutes)
1 finding from 1 review
Direct healthcare costs (USD equivalent)
1 finding from 1 review
Adverse events
Electromagnetic‐guided showed no clear difference in adverse events compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (moderate certainty).
1 finding from 1 review