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Evidence found and GRADE certainty

182 questions · 183 findings · 20 reviews · Headline outcomes only

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No studies found 46 · 25.1%GRADE not reported 5 · 2.7%Very low 51 · 27.9%Low 37 · 20.2%Moderate 34 · 18.6%High 10 · 5.5%

Intervention not reported

Parasite prevalence (21‐ to 25‐month · adults and childen living in malaria‐endemic areas, Anopheles gambiae complex or Anopheles funestus group

The intervention probably leads to lower parasite prevalence (21‐ to 25‐month (moderate certainty).

1 finding from 1 review

Intervention not reported

Mosquito mortality (washed nets) · adults and childen living in malaria‐endemic areas, Anopheles gambiae complex or Anopheles funestus group

It is very uncertain whether the intervention changes mosquito mortality (washed nets) (very low certainty).

1 finding from 1 review

Oral iron sulphate vs oral iron hydroxide polymaltose complex

Serious adverse events ‐ active or inactive disease (14 days) · IBD patients

It is very uncertain whether oral iron sulphate changes serious adverse events ‐ active or inactive disease (14 days) compared with oral iron hydroxide polymaltose complex (very low certainty).

1 finding from 1 review

Intervention not reported

50% reduction of tumour sizea · people with TSC

The intervention leads to higher 50% reduction of tumour sizea (high certainty).

1 finding from 1 review

Intervention not reported

Frequency of seizure · people with TSC

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Creatinine level · people with TSC

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

FEV1/FVC ratio · people with TSC

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · people with TSC

The intervention probably leads to higher adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Response to skin lesionsb · people with TSC

The intervention leads to higher response to skin lesionsb (high certainty).

1 finding from 1 review

Intervention not reported

Frequency of seizure · people with TSC

The intervention probably leads to higher frequency of seizure (moderate certainty).

1 finding from 1 review

Intervention not reported

Number of participants with an increased creatinine level · people with TSC

The intervention probably leads to lower number of participants with an increased creatinine level (moderate certainty).

1 finding from 1 review

Intervention not reported

FEV1/FVC ratio · people with TSC

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · people with TSC

The intervention leads to higher adverse events (high certainty).

1 finding from 1 review