Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

138 questions · 141 findings · 9 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 27 · 19.1%GRADE not reported 4 · 2.8%Very low 25 · 17.7%Low 53 · 37.6%Moderate 27 · 19.1%High 5 · 3.5%

Summary of findings 2: PLD alone vs other conventional chemotherapy

Overall severe adverse events (grade > 3) · recurrent platinum‐resistant EOC

It is very uncertain whether summary of findings 2: PLD alone changes overall severe adverse events (grade > 3) compared with other conventional chemotherapy (very low certainty).

1 finding from 1 review

Summary of findings 2: PLD alone vs other conventional chemotherapy

Hand‐foot syndrome (grade ≥ 3) · recurrent platinum‐resistant EOC

It is very uncertain whether summary of findings 2: PLD alone changes hand‐foot syndrome (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

The incidence and severity of toxicities: leukopenia (WHO grade 3 to 4) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in the incidence and severity of toxicities: leukopenia (WHO grade 3 to… compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Patient‐reported symptom: nausea/vomiting (WHO grade 3 to 4) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment may leads to lower patient‐reported symptom: nausea/vomiting (WHO grade 3 to 4) compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Diarrhoea · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in patient‐reported symptom: diarrhoea compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Haemoglobin (g/dL) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment may leads to higher objective outcome measure: haemoglobin (g/L) compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Objective outcome measure: platelets (× 109/L) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in objective outcome measure: platelet (× 109/L) compared with conventional medicine alone (low certainty).

1 finding from 1 review