Benzodiazepines vs placebo
It is very uncertain whether comparison 5: benzodiazepines changes dropouts due to adverse events (acute phase) compared with placebo (very low certainty).
- RR 1.68 [0.21, 13.13]2 studies · 96 participantsVery low
It is very uncertain whether comparison 5: benzodiazepines changes dropouts due to adverse events (acute phase) compared with placebo (very low certainty).
Lamotrigine showed no clear difference in recurrence of any episodes at one year for clinical worsening with… compared with lithium (moderate certainty).
Lamotrigine probably leads to lower recurrence of any episodes at one year for clinical worsening with… compared with placebo (moderate certainty).
Antidepressants showed no clear difference in failure to respond compared with benzodiazepines (low certainty).
TCAs may leads to higher number of dropouts due to adverse effects compared with benzodiazepines (low certainty).
It is very uncertain whether SSRIs changes failure to respond compared with benzodiazepines (very low certainty).
It is very uncertain whether SSRIs changes total number of dropouts compared with benzodiazepines (very low certainty).
It is very uncertain whether SSRIs changes failure to remit compared with benzodiazepines (very low certainty).
It is very uncertain whether SSRIs changes number of dropouts due to adverse effects compared with benzodiazepines (very low certainty).
It is very uncertain whether antidepressants changes total number of dropouts compared with benzodiazepines (very low certainty).
Antidepressants probably leads to higher failure to remit compared with benzodiazepines (moderate certainty).
Antidepressants may leads to higher number of dropouts due to adverse effects compared with benzodiazepines (low certainty).
It is very uncertain whether TCAs changes failure to respond compared with benzodiazepines (very low certainty).
It is very uncertain whether TCAs changes total number of dropouts compared with benzodiazepines (very low certainty).