Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,368 questions · 1,413 findings · 89 reviews · Common Mental Disorders

No studies found 232 · 16.4%GRADE not reported 82 · 5.8%Very low 395 · 28%Low 331 · 23.4%Moderate 341 · 24.1%High 32 · 2.3%

Amitriptyline vs placebo

Adverse effects (drop‐outs due to adverse effects4) · adults with Major Depressive Disorder

Amitriptyline probably leads to higher overall tolerability Drop‐out due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Self‐efficacy score Scale: Generalized Self‐Efficacy Scale Direction: higher better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Intervention not reported

Dropouts from treatment · women aged 16 years and older who self‐report previous or current experience of intimate partner violence

The intervention showed no clear difference in dropouts from treatment (low certainty).

1 finding from 1 review

Intervention not reported

Post‐traumatic stress disorder Score Scale: Clinician Administered PTSD Scale, Posttraumatic Stress Symptoms— Interview, Posttraumatic Stress Disorder Checklist Direction: lower better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Intervention not reported

Re‐exposure to IPV score Scales: Revised Conflict Tactics Scales, Composite Abuse Scale Direction: lower better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Intervention not reported

Safety planning and/or safety behaviour score Service use and activities questionnaire Direction: higher better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term remission · adults with panic disorder

All psychological therapies showed no clear difference in short‐term remission compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

1 finding from 1 review

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term response · adults with panic disorder

All psychological therapies showed no clear difference in short‐term response compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

1 finding from 1 review