Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,835 questions · 1,886 findings · 74 reviews · Skin

No studies found 542 · 28.7%GRADE not reported 130 · 6.9%Very low 326 · 17.3%Low 434 · 23%Moderate 348 · 18.5%High 106 · 5.6%

Topical active treatment in combination with moisturiser vs topical active treatment alone

Number of participants reporting an adverse event · people with eczema

It is very uncertain whether topical active treatment in combination with moisturiser changes number of participants reporting an adverse event compared with topical active treatment alone (very low certainty).

1 finding from 1 review

Atopiclair vs vehicle

Change from baseline in disease severity as assessed by the participants (number of participants who considered their skin to have improved) · people with eczema

Atopiclair probably leads to higher change from baseline in disease severity according to participants… compared with vehicle (moderate certainty).

1 finding from 1 review

Complete cure and adverse events for terbinafine vs griseofulvin

Proportion of participants with complete cure · children with tinea capitis

Complete cure and adverse events for terbinafine showed no clear difference in proportion of participants with complete cure compared with griseofulvin (low certainty).

4 findings from 1 review
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Complete cure for ketoconazole vs griseofulvin

Proportion of participants with complete cure · children infected with Trichophyton

Complete cure for ketoconazole showed no clear difference in proportion of participants with complete cure compared with griseofulvin (low certainty).

2 findings from 1 review

Complete cure for fluconazole vs griseofulvin

Proportion of participants with complete cure · children with tinea capitis

Complete cure for fluconazole showed no clear difference in proportion of participants with complete cure compared with griseofulvin (moderate certainty).

2 findings from 1 review

Intervention not reported

Proportion of participants with complete cure · children infected with T. tonsurans and M. canis

The intervention showed no clear difference in proportion of participants with complete cure (low certainty).

1 finding from 1 review