Findings

What do systematic reviews say?

1,763 questions · 1,835 findings · 201 reviews · Headline outcomes only

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No studies found 414 · 22.6%GRADE not reported 51 · 2.8%Very low 570 · 31.1%Low 468 · 25.5%Moderate 272 · 14.8%High 60 · 3.3%

Intervention not reported

Dietary advice plus exercise advice(1 trial; 265 participants) (another trial 25 participants had zero events in both groups) · people with nonalcohol‐related fatty liver disease (NAFLD)

It is very uncertain whether the intervention changes dietary advice plus exercise advice(1 trial; 265 participants)… (very low certainty).

1 finding from 1 review

Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
HR 0.63
Studies not reported
Very low

Intervention not reported

Aerobic exercise plus calorie‐restricted diet(1 trial; 100 participants) · people with nonalcohol‐related fatty liver disease (NAFLD)

1 finding from 1 review

Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Aerobic exercise plus dietary advice(1 trial; 154 participants) · people with nonalcohol‐related fatty liver disease (NAFLD)

1 finding from 1 review

Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Resistance exercise(1 trial; 45 participants) · people with nonalcohol‐related fatty liver disease (NAFLD)

1 finding from 1 review

Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Stem cell therapy vs peripheral therapy with granulocyte colony‐stimulating factor

Functional capacityAssessed: 6MWT · DCM (non‐ischaemic)

1 finding from 1 review

Stem cell therapy for dilated cardiomyopathy 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 155 participants
Low

Supervised maintenance programme following pulmonary rehabilitation vs usual care

Six‐minute walk distance · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Supervised maintenance programmes following pulmonary rehabilitation compared to usual care for chronic obstructive… 2021 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 639 participants
Low

Pentoxifylline vs placebo

ABI (pre‐exercise/baseline ABI compared with · intermittent claudication

1 finding from 1 review

Pentoxifylline for intermittent claudication 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 902 participants
Moderate

Respiratory muscle training vs control

Exercise capacity · adults and children with cystic fibrosis

1 finding from 1 review

Respiratory muscle training for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 54 participants
Very low

Motor neuroprosthesis vs another assistive technology device

Exercise capacity · promoting recovery of function after stroke

1 finding from 1 review

Motor neuroprosthesis for promoting recovery of function after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 692 participants
Low

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Exercise capacity · adults (≥ 18 years of age) with a diagnosis of chronic heart failure with reduced ejection fraction (HFrEF)

2 findings from 1 review

Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 305 participants
Low
Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 158 participants
Low

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Exercise capacity · patients with chronic heart failure with preserved ejection fraction

2 findings from 1 review

Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 179 participants
Low
Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 171 participants
Low

Inhaled corticosteroids vs placebo

Change in exercise tolerance · adults and children with cystic fibrosis

1 finding from 1 review

Inhaled corticosteroids for cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Summary of findings ‐ PEP vs oscillating PEP

Exercise capacity · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 68 participants
Moderate

Summary of findings ‐ PEP vs HFCWO

Exercise capacity · adults and children with CF

The review found no eligible studies for this question.

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ PEP vs BiPAP

Exercise capacity · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Low

Summary of findings ‐ PEP vs airway clearance techniques

Exercise capacity · adults and children with cystic fibrosis

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Low

Summary of findings ‐ PEP vs PDPV

Exercise capacity · adults and children with CF

1 finding from 1 review

Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 66 participants
Low

Psychological therapies vs education

Change in exercise tolerance · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 286 participants
Very low

Psychological therapies vs no intervention

Change in exercise tolerance · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Nurse‐led care vs doctor‐led care

Exercise capacity · management of bronchiectasis

1 finding from 1 review

Nurse‐led versus doctor‐led care for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low