Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Oral vs vaginal administration of oestradiol and dydrogesterone

Endometrial thickness (mm) · women with premature ovarian insufficiency (POI) awaiting oocyte donation
2 findings from 1 review

Enhanced recovery protocol vs traditional care

Overall postoperative complications (within 30 days of operation) · women with gynaecological cancers

Enhanced recovery after surgery programme showed no clear difference in overall postoperative complications (within 30 days of operation) compared with traditional care (low certainty).

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term complications (abscess, perforation, obstruction or fistula) within 30 days · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in primary ‐ Short‐term complications (abscess, perforation,… (low certainty).

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term complications (abscess, perforation, obstruction or fistula) within 30 days · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in primary ‐ Short‐term emergency surgery within 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term complications (abscess, perforation, obstruction or fistula) within 30 days · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Primary ‐ Short‐term emergency surgery within 30 days · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in primary ‐ Short‐term emergency surgery within 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Failure of re‐epithelialisation by day 21 post‐injury Image analysis of digital photographs · people with moderate acute ocular burns

It is very uncertain whether the intervention changes failure of re‐epithelialisation by day 21 post‐injury Image analysis… (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of re‐epithelialisation by day 21 post‐injury Image analysis of digital photographs · people with severe acute ocular burns

The intervention showed no clear difference in failure of re‐epithelialisation by day 21 post‐injury Image analysis… (low certainty).

1 finding from 1 review

Helium vs carbon dioxide

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

Helium showed no clear difference in pain scores (first postoperative day) Visual analogue scale, lower… compared with carbon dioxide (low certainty).

1 finding from 1 review

Room air vs carbon dioxide

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether room air changes pain scores (first postoperative day) Visual analogue scale, lower… compared with carbon dioxide (very low certainty).

1 finding from 1 review

Nitrous oxide vs carbon dioxide

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether nitrous oxide changes pain scores (first postoperative day) VAS, lower score indicates… compared with carbon dioxide (very low certainty).

1 finding from 1 review