Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

PIMOZIDE vs placebo

Adverse effects: extrapyramidal adverse effects Parkinsonism (rigidity) short term (< 3 months) Extrapyramidal Symptom Rating Scale (ESRS) · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes adverse effects: extrapyramidal adverse effects: Parkinsonism… compared with PLACEBO (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with premature beat: Shortscape Fleabane injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis

The intervention showed no clear difference in number of patients with premature beat: Shortscape Fleabane… (low certainty).

1 finding from 1 review

Posterior cruciate ligament retention vs sacrifice (using the same arthroplasty design)

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without resection of the posterior cruciate ligament for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs posterior stabilised sacrifice

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs sacrifice (all types of arthroplasty designs)

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

DANCE THERAPY vs usual care

Clinical global response‐leaving the study early (short term) · patients with schizophrenia

DANCE THERAPY showed no clear difference in clinical global response‐leaving the study early (short term) compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Intervention not reported

Functional status, short term Oswestry Disability Index (ODI 0 to 100%) or Roland Morris (0 to 24) · participants with lumbar spinal stenosis
1 finding from 1 review

Intervention not reported

Low back pain, short term Visual analogue scale (VAS 0 to 100) · participants with lumbar spinal stenosis
1 finding from 1 review

Selenium (+LT4) vs placebo (+LT4)

Change from baseline in assessment of symptoms such as mood, fatigue and muscle weakness Short‐Form Health Survey · participants with Hashimoto's thyroiditis.

Selenium (+LT4) may leads to higher change from baseline in assessment of symptoms such as mood, fatigue… compared with placebo (+LT4) (low certainty).

1 finding from 1 review

Intervention not reported

Pain Intensity ‐ short‐term · Patients with subacute/chronic mechanical neck pain
1 finding from 1 review

Intervention not reported

Pain Intensity: Short term · Patients with unknown duration of mechanical neck pain
1 finding from 1 review