Findings

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Evidence found and GRADE certainty

4,730 questions · 18,059 findings · 1,282 reviews

No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

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Farzanegan 2021 = Transbond XT + 1% chitosan + 1% TiO2 (co-intervention); Mollabashi 2022 = TiO2-only composite (1 wt%) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel demineralization / white spot lesion prevention (DIAGNOdent, enamel mineral content) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)

Two small RCTs gave inconsistent results for TiO2-modified adhesives/composites on enamel demineralization (one favorable on DIAGNOdent, one no difference in mineral content); ungraded.

1 finding from 1 review

Infliximab combined with purine analogues vs purine analogues

Clinical relapse · Participants with Crohn's disease in remission

Infliximab combined with purine analogues probably leads to lower clinical relapse (at 48 weeks, CDAI of 150 or greater together with… compared with purine analogues (moderate certainty).

1 finding from 1 review

Intervention not reported

Failure of hemostatic intervention ( · vascular surgery patients who undergo creation of an anastomosis

It is very uncertain whether the intervention changes failure of hemostatic intervention ( (very low certainty).

1 finding from 1 review

Intervention not reported

Finding 16. Accessible, sustainable interventions and finding the right type of exercise were all identified as important. For many women and men with bipolar disorder, the right type of exercise was walking. · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 20. There are some considerations for designing interventions that promote physical activity for bipolar disorder. These include sequencing multicomponent lifestyle changes, technology, incentives, and health promotion strategies that are ... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review