Cochrane · systematic review · CD013421
The role of sealants for achieving anastomotic hemostasis in vascular surgery
Ma, G-W, Kucey, A, Tyagi, SC, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Are sealants better than standard care for achieving hemostasis in vascular surgery?
Population: vascular surgery patients who undergo creation of an anastomosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to hemostasis (seconds) | no estimate extracted | 7 studies · 498 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Failure of hemostatic intervention ( | RR 0.46 [0.35, 0.61] | 17 studies · 2120 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Intraoperative blood loss (mL) | no estimate extracted | 3 studies · 266 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Operating time (minutes) | no estimate extracted | 4 studies · 436 participants | Low Downgraded: risk of bias, imprecision |
Death from bleeding complications (up to 30 days | no estimate extracted | NR | No studies |
Postoperative bleeding (up to 30 days | RR 0.78 [0.59, 1.04] | 9 studies · 1216 participants | Low Downgraded: risk of bias, imprecision |
Unplanned return to the operating room (up to 30 days | RR 0.27 [0.04, 1.69] | 8 studies · 721 participants | Low Downgraded: risk of bias, imprecision |