What do systematic reviews say?

Short‐acting inhaled beta‐2 agonists vs placebo

It is very uncertain whether short‐acting inhaled beta‐2 agonists changes participant‐reported symptom score: cough, wheeze and exercise… compared with placebo (very low certainty).

• Short‐acting inhaled bronchodilators for cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 22 participants
  Very low

Coenzyme Q10 vs placebo or conventional therapy

• Coenzyme Q10 for heart failure 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 91 participants
  Very low

Integrated disease management interventions vs usual care

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 2071 participants
  Moderate

Autogenic drainage vs spontaneous cough

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs active cycle of breathing technique

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Low

Autogenic drainage vs PEP

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs Cornet®

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs Flutter®

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs conventional physiotherapy

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs high frequency chest wall oscillation

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs intrapulmonary percussive ventilation (200 bpm)

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autogenic drainage vs intrapulmonary percussive ventilation (400 bpm)

The review found no eligible studies for this question.

• Autogenic drainage for airway clearance in cystic fibrosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Telerehabilitation vs no rehabilitation control

Telerehabilitation may leads to higher exercise capacity ‐ 6MWD (m) compared with no rehabilitation control (low certainty).

• Telerehabilitation for chronic respiratory disease 2021 · Cochrane Headline outcomes only
  MD 78.1 [49.6, 106.6]
  2 studies · 209 participants
  Low
• Telerehabilitation for chronic respiratory disease 2021 · Cochrane Headline outcomes only
  MD 22.17
  2 studies · 94 participants
  Low

Telerehabilitation vs centre‐based (outpatient) pulmonary rehabilitation

Telerehabilitation showed no clear difference in exercise capacity ‐6MWD (m) compared with centre‐based (outpatient) pulmonary rehabilitation (moderate certainty).

• Telerehabilitation for chronic respiratory disease 2021 · Cochrane Headline outcomes only
  MD 0.06
  4 studies · 556 participants
  Moderate

Intervention not reported

• Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low