Number of new occurrences of RBC transfusion · patients with vitamin K antagonist‐induced bleeding requiring acute intervention
It is very uncertain whether prothrombin complex concentrate changes number of new occurrences of RBC transfusion compared with any comparator (very low certainty).
1 finding from 1 review
Transfusion of RBCs · patients with vitamin K antagonist‐induced bleeding requiring acute intervention
1 finding from 1 review
Intervention not reported
Death ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention showed no clear difference in death ( (moderate certainty).
1 finding from 1 review
Intervention not reported
Arterial thromboembolic events ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention probably leads to higher arterial thromboembolic events ( (moderate certainty).
1 finding from 1 review
Intervention not reported
Total operative and perioperative blood loss (mL) ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
1 finding from 1 review
Intervention not reported
Red cell transfusion requirements (mL) ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
1 finding from 1 review
Intervention not reported
Number of patients transfused ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention showed no clear difference in number of patients transfused ( (low certainty).
1 finding from 1 review
Intervention not reported
Total thromboembolic events ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention showed no clear difference in total thromboembolic events ( (moderate certainty).
1 finding from 1 review
Intervention not reported
Death ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention showed no clear difference in death ( (moderate certainty).
1 finding from 1 review
Intervention not reported
Numbers of patients with reduced bleeding ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention showed no clear difference in numbers of patients with reduced bleeding ( (low certainty).
1 finding from 1 review
Intervention not reported
Red cell transfusion requirements (mL) ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
1 finding from 1 review
Intervention not reported
Total thromboembolic events ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…
The intervention showed no clear difference in total thromboembolic events ( (moderate certainty).
1 finding from 1 review
Length of hospital stay · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
The review found no eligible studies for this question.
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether physiotherapy (tongue-spatula jaw exercises) changes maximal mouth opening (interincisal distance) compared with no active treatment (very low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Intralesional steroid injection plus adjunctive treatment showed no clear difference in maximal mouth opening (interincisal distance) compared with intralesional steroid injection alone (low certainty).
2 findings from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether topical curcumin gel changes maximal mouth opening (interincisal distance) compared with topical aloe vera gel (very low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether buccal fat pad pedicle plus placental extract changes maximal mouth opening (interincisal distance) compared with buccal fat pad pedicle alone (very low certainty).
1 finding from 1 review
Participant-reported resumption of normal eating, chewing and speech · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether vasodilators (isoxsuprine, xanthinol nicotinate) changes maximal mouth opening (interincisal distance) compared with placebo or no active treatment (very low certainty).
2 findings from 1 review