Findings

What do systematic reviews say?

1,166 questions · 1,249 findings · 76 reviews

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No studies found 378 · 30.3%GRADE not reported 61 · 4.9%Very low 377 · 30.2%Low 284 · 22.7%Moderate 120 · 9.6%High 29 · 2.3%

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Reduction in total serum cholesterol at ≤ 6 months (mg/dL) · People receiving lipid‐lowering medications

1 finding from 1 review

Interventions to improve adherence to lipid‐lowering medication 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 430 participants
Low

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Reduction in total serum cholesterol at > 6 mos (mg/dL) · People receiving lipid‐lowering medications

1 finding from 1 review

Interventions to improve adherence to lipid‐lowering medication 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 127 participants
High

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Aggressive behaviour: aggressive events – carer reports – post‐training (Analysis 4.1) · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 128 participants
Low

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Ability to control anger ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Adaptive functioning ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Mental state ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Quality of life ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mindfulness based on positive behaviour support vs positive behaviour support

Cost of service utilisation ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

DFP and DFO vs DFP

Adherence to iron chelation therapy (%, SD)

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 369 participants
Low

DFP and DFO vs DFP

SAEs

Summary of findings: Comparison 5 ‐ deferiprone (DFP) plus… showed no clear difference in incidence of SAEs compared with DFP (low certainty).

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
RR 0.15 [0.01, 2.81]
1 study · 213 participants
Low

DFP and DFO vs DFP

All‐cause mortality

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
0.77 [0.17, 3.42]
2 studies · 237 participants
Very low

DFP and DFO vs DFP

Sustained adherence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

DFP and DFO vs DFP

QoL

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

DFP and DFO vs deferoxamine

Adherence to iron chelation therapy (%, SD)

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 281 participants
Low

DFP and DFO vs deferoxamine

SAEs

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 180 participants
Low

DFP and DFO vs deferoxamine

All‐cause mortality

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

DFP and DFO vs deferoxamine

Sustained adherence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

DFP and DFO vs deferoxamine

QoL

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

DFP and DFO vs DFP and DFX

Adherence to iron chelation therapy ‐ not reported

Summary of findings: Comparison 7 ‐ deferiprone (DFP) plus… may leads to lower adherence to iron chelation therapy rates (n, N) compared with DFP plus deferasirox (DFX) (low certainty).

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
RR 0.84 [0.72, 0.99]
1 study · 96 participants
Low

DFP and DFO vs DFP and DFX

SAEs

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
1 [0.06, 16.22]
1 study · 96 participants
Very low