Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,411 questions · 1,474 findings · 170 reviews

No studies found 336 · 22.8%GRADE not reported 97 · 6.6%Very low 419 · 28.4%Low 395 · 26.8%Moderate 188 · 12.8%High 39 · 2.6%

Cannabis‐based medicines vs placebo medication

Daily breakthrough opioid dosage (mg morphine equivalent) · adults with cancer‐related pain

Cannabis‐based medicines showed no clear difference in daily breakthrough opioid dosage (mg morphine equivalent) compared with placebo medication (moderate certainty).

1 finding from 1 review

Mifepristone (600 mg) plus prostaglandin vs mifepristone (200 mg) plus prostaglandin

Failure to achieve complete abortion · women undergoing first trimester abortion

Mifepristone (600 mg) plus prostaglandin showed no clear difference in failure to achieve complete abortion compared with mifepristone (200 mg) plus prostaglandin (moderate certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Failure to achieve complete abortion · women undergoing first trimester abortion

Oral misoprostol probably leads to higher failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).

2 findings from 1 review

Sublingual misoprostol vs vaginal misoprostol

Women's dissatisfaction with the procedure · women undergoing first trimester abortion

Sublingual misoprostol showed no clear difference in women's dissatisfaction with the procedure compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review