Oral misoprostol vs vaginal misoprostol: Failure to achieve complete abortion
Oral misoprostol probably leads to higher failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral misoprostol vs vaginal misoprostol Failure to achieve complete abortion · women undergoing first trimester abortion Oral misoprostol probably leads to higher failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty). Medical methods for first trimester abortion (2022) · Cochrane Headline outcomes only | RR 2.38 [1.46, 3.87] | 3 studies · 1704 participants | Moderate |
Oral misoprostol alone vs vaginal misoprostol alone Failure to achieve complete abortion · women undergoing first trimester abortion Oral misoprostol alone may leads to higher failure to achieve complete abortion compared with vaginal misoprostol alone (low certainty). Medical methods for first trimester abortion (2022) · Cochrane Headline outcomes only | RR 3.68 [1.56, 8.71] | 2 studies · 216 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.